The TRAPP complexes: oligomeric exchange factors that activate the small GTPases Rab1 and Rab11
Sign Up to like & getrecommendations! Published in 2022 at "Febs Letters"
DOI: 10.1002/1873-3468.14553
Abstract: The Transport Protein Particle (TRAPP) complexes are highly conserved multisubunit complexes that act as nucleotide exchange factors (GEFs) for Rab GTPases. They act in both protein secretion and autophagy and have also been proposed to… read more here.
Keywords: trapp complexes; complexes oligomeric; oligomeric exchange; exchange factors ... See more keywords
The TRAPP complexes: discriminating GTPases in context
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DOI: 10.1002/1873-3468.14557
Abstract: Correct localization of Rab GTPases in cells is critical for proper function in membrane trafficking. Guanine‐nucleotide exchange factors (GEFs) act as the primary determinants of Rab localization by activating and stabilizing their Rab substrates on… read more here.
Keywords: trapp complexes; rab; complexes discriminating; discriminating gtpases ... See more keywords
TRAPPopathies: Severe Multisystem Disorders Caused by Variants in Genes of the Transport Protein Particle (TRAPP) Complexes
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DOI: 10.3390/ijms252413329
Abstract: The TRAPP (TRAnsport Protein Particle) protein complex is a multi-subunit complex involved in vesicular transport between intracellular compartments. The TRAPP complex plays an important role in endoplasmic reticulum-to-Golgi and Golgi-to-plasma membrane transport, as well as… read more here.
Keywords: disease; protein particle; transport protein; trapp complex ... See more keywords