Biochemical insight into novel Rab-GEF activity of the mammalian TRAPPIII complex.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.167145
Abstract: Transport Protein Particle complexes (TRAPP) are evolutionarily conserved regulators of membrane trafficking, with this mediated by their guanine nucleotide exchange factor (GEF) activity towards Rab GTPases. In metazoans evidence suggests that two different TRAPP complexes… read more here.
Keywords: trappiii complex; trappii; activity; gef activity ... See more keywords
Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43207
Abstract: The Transport protein particle (TRAPP) complex is a tethering factor for COPII vesicle. Of three forms of TRAPP (TRAPPI, II and III) complexes identified so far, TRAPPIII has been largely considered to play a role… read more here.
Keywords: trappiii; mammalian trappiii; trappiii complex; copii ... See more keywords