Profiling biomarkers of traumatic axonal injury: From mouse to man
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2018.05.017
Abstract: Traumatic brain injury (TBI) poses a major public health problem on a global scale. Its burden results from high mortality and significant morbidity in survivors. This stems, in part, from an ongoing inadequacy in diagnostic… read more here.
Keywords: traumatic axonal; biomarkers traumatic; axonal injury; tbi ... See more keywords
Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2017.11.001
Abstract: ABSTRACT Since traumatic axonal injury (TAI) is implicated as a prominent pathology of concussion, we examined potential sex differences in axon structure and responses to TAI. Rat and human neurons were used to develop micropatterned… read more here.
Keywords: female axons; traumatic axonal; axonal injury; pathology ... See more keywords
Microglia: A Potential Drug Target for Traumatic Axonal Injury
Sign Up to like & getrecommendations! Published in 2021 at "Neural Plasticity"
DOI: 10.1155/2021/5554824
Abstract: Traumatic axonal injury (TAI) is a major cause of death and disability among patients with severe traumatic brain injury (TBI); however, no effective therapies have been developed to treat this disorder. Neuroinflammation accompanying microglial activation… read more here.
Keywords: traumatic axonal; axonal injury; drug target; potential drug ... See more keywords