Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-018-2031-9
Abstract: The onset of acute traumatic coagulopathy in trauma patients exacerbates hemorrhaging and dramatically increases mortality. The disease is characterized by increased localized bleeding, and the mechanism for its onset is not yet known. We propose… read more here.
Keywords: computational model; onset acute; acute traumatic; traumatic coagulopathy ... See more keywords
Acute traumatic coagulopathy: pathophysiology and resuscitation.
Sign Up to like & getrecommendations! Published in 2017 at "British journal of anaesthesia"
DOI: 10.1093/bja/aex281
Abstract: Acute Traumatic Coagulopathy occurs immediately after massive trauma when shock, hypoperfusion, and vascular damage are present. Mechanisms for this acute coagulopathy include activation of protein C, endothelial glycocalyx disruption, depletion of fibrinogen, and platelet dysfunction.… read more here.
Keywords: damage control; traumatic coagulopathy; acute traumatic; pathophysiology ... See more keywords
A prospective evaluation of thromboelastometry (ROTEM) to identify acute traumatic coagulopathy and predict massive transfusion in military trauma patients in Afghanistan
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DOI: 10.1111/trf.15176
Abstract: Hemorrhage is the leading cause of preventable trauma‐related mortality and is frequently aggravated by acute traumatic coagulopathy (ATC). Viscoelastic tests such as rotational thromboelastometry (ROTEM) may improve identification and management of ATC. This study aimed… read more here.
Keywords: thromboelastometry; traumatic coagulopathy; thromboelastometry rotem; acute traumatic ... See more keywords
A prospective observational study of acute traumatic coagulopathy in traumatic bleeding from the battlefield
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DOI: 10.1111/trf.15658
Abstract: Acute trauma coagulopathy (ATC) after military trauma has not been comprehensively studied. ATC is defined as a prolonged prothrombin time ratio (PTr) or reduced clot amplitude (A5) in viscoelastic testing. Compared to civilian trauma, military… read more here.
Keywords: observational study; prospective observational; traumatic coagulopathy; trauma ... See more keywords
G332 Acute traumatic coagulopathy in the paediatric population: a systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2018-rcpch.322
Abstract: Introduction Acute traumatic coagulopathy is a clinically distinct coagulopathy resulting from the injury itself and subsequent hypoperfusion. The condition has been associated with increased morbidity and mortality in adults but little is known about the… read more here.
Keywords: coagulopathy paediatric; traumatic coagulopathy; acute traumatic; review ... See more keywords
Integrated single-cell multiomics reveals novel immune candidate markers for post-traumatic coagulopathy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1095657
Abstract: Introduction Post-traumatic coagulopathy (PTC) is a critical pathology in traumatic brain injury (TBI), however, its potential mechanism is not clear. To explore this in peripheral samples, we integrated single cell RNA-sequencing and T cell repertoire… read more here.
Keywords: cell; traumatic coagulopathy; single cell; integrated single ... See more keywords