Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK‐906), a Novel Selective D2/D3 Receptor Antagonist: A Phase 1 Randomized, Placebo‐Controlled Single‐ and Multiple‐Dose Escalation Study in Healthy Participants
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DOI: 10.1002/cpdd.906
Abstract: Gastroparesis is a chronic neuromuscular disorder of the upper gastrointestinal tract in which episodic exacerbation can lead to frequent hospitalizations and severe disability. Dopamine D2/D3 receptor antagonists have been used to treat patients with gastroparesis… read more here.
Keywords: receptor antagonist; trazpiroben tak; healthy participants; safety ... See more keywords