TRBP modulates RLR signaling by inhibiting PKR-mediated antiviral stress granule formation
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DOI: 10.1038/s41598-025-07121-3
Abstract: Stress granules (SGs) are dense aggregates of RNA and proteins that form in response to various cellular stresses. Virus-induced SGs, known as antiviral SGs (avSGs), play a crucial role in regulating retinoic acid-inducible gene I-like… read more here.
Keywords: trbp; stress; rna; avsg formation ... See more keywords
Differential regulation of ATP hydrolysis of RIG-I-like receptors by transactivation response RNA-binding protein
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DOI: 10.1042/bsr20222152
Abstract: Abstract Retinoic acid inducible gene (RIG)-I-like receptors (RLRs), including RIG-I, melanoma differentiation associated-5 (MDA5), and laboratory of genetics and physiology 2 (LGP2), play pivotal roles in viral RNA sensing to initiate antiviral interferon (IFN) responses.… read more here.
Keywords: rna; trbp; atp hydrolysis; response ... See more keywords