Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells
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DOI: 10.3389/fmed.2022.845918
Abstract: Endoglin (Eng) is a co-receptor of the transforming growth factor β superfamily playing an important role in endothelial dysfunction. TRC105 (carotuximab) is a monoclonal antibody that blocks Eng and its downstream Smad signaling pathway. Here… read more here.
Keywords: trc105 carotuximab; dysfunction; hyperglycemia; human aortic ... See more keywords