Diagnosis of uncommon renal epithelial neoplasms: performances of fluorescence in situ hybridization.
Sign Up to like & getrecommendations! Published in 2019 at "Human pathology"
DOI: 10.1016/j.humpath.2019.08.005
Abstract: Renal cell carcinomas (RCC) are divided in several subtypes, characterized by morphological and histological features, protein expression patterns and genetics criteria. The main subtypes include Clear cell renal cell carcinoma (CCRCC), Papillary RCC (PRCC), Chromophobe… read more here.
Keywords: diagnosis; fluorescence situ; rcc; trcc ... See more keywords
Therapeutic Targeting of TFE3/IRS-1/PI3K/mTOR Axis in Translocation Renal Cell Carcinoma
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DOI: 10.1158/1078-0432.ccr-18-0269
Abstract: Purpose: Translocation renal cell carcinoma (tRCC) represents a rare subtype of kidney cancer associated with various TFE3, TFEB, or MITF gene fusions that are not responsive to standard treatments for RCC. Therefore, the identification of… read more here.
Keywords: pi3k; trcc; mtor; translocation renal ... See more keywords
Gene Expression Analysis of Aggressive Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical Stage T1N0M0 to Identify Potential Prognostic and Therapeutic Biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020321
Abstract: Xp11.2 translocation renal cell carcinoma (tRCC), involving transcription factor E3 (TFE3) gene fusions, is a rare and aggressive RCC variant when present in adults and has been recently recognized as a unique entity in RCC.… read more here.
Keywords: cell; xp11; trcc; xp11 trcc ... See more keywords
MiTF/TFE Translocation Renal Cell Carcinomas: From Clinical Entities to Molecular Insights
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DOI: 10.3390/ijms23147649
Abstract: MiTF/TFE translocation renal cell carcinoma (tRCC) is a rare and aggressive subtype of RCC representing the most prevalent RCC in the pediatric population (up to 40%) and making up 4% of all RCCs in adults.… read more here.
Keywords: renal cell; mitf tfe; trcc; tfe translocation ... See more keywords