NUMB facilitates autophagy initiation through targeting SCFβ-TrCP2 complex.
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DOI: 10.1038/s41418-022-00930-3
Abstract: Given the critical role of SCF E3 ligases in autophagy by modulating the protein stability of various autophagic components, the activity of SCF should be tightly controlled to maintain the autophagic flux. We here showed… read more here.
Keywords: protein abundance; scf trcp2; numb facilitates; trcp2 ... See more keywords