Clinical efficacy of trauma-focused psychotherapies in treatment-resistant depression (TRD) in-patients: A randomized, controlled pilot-study
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2019.01.070
Abstract: In major depressive disorder (MDD) patients, life stress events represent a risk factor for a severe, early-onset, treatment-resistant and chronic endophenotype. Treatment-resistant depression (TRD) patients who have experienced traumatic events could benefit from evidence-based trauma-focused… read more here.
Keywords: trauma focused; treatment resistant; trd; focused psychotherapies ... See more keywords
Antidepressant Effect of Ketamine on Inflammation-Mediated Cytokine Dysregulation in Adults with Treatment-Resistant Depression: Rapid Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1061274
Abstract: Background Major depressive disorder (MDD) and treatment-resistant depression (TRD) represent a global source of societal and health burden. To advise proper management of inflammation-related depression among TRD patients, it is important to identify therapeutic clinical… read more here.
Keywords: trd patients; ketamine; depression; antidepressant effect ... See more keywords
Age as a moderating factor of treatment resistance in depression
Sign Up to like & getrecommendations! Published in 2023 at "European Psychiatry"
DOI: 10.1192/j.eurpsy.2023.17
Abstract: Abstract Background Treatment-resistant depression (TRD) is an important clinical challenge and may present differently between age groups. Methods A total of 893 depressed patients recruited within the framework of the European research consortium “Group for… read more here.
Keywords: trd patients; depression; age; age moderating ... See more keywords
Abnormal Prefrontal Brain Activation During a Verbal Fluency Task in Treatment-Resistant Depression Using Near-Infrared Spectroscopy
Sign Up to like & getrecommendations! Published in 2023 at "Psychiatry Investigation"
DOI: 10.30773/pi.2021.0372
Abstract: Objective The study investigated cognitive performance and brain function between treatment-resistant depression (TRD) and non-TRD patients to find potential neurobiological markers associated with refractoriness in depression patients. Methods Fourteen TRD patients, 26 non-TRD patients and… read more here.
Keywords: trd patients; spectroscopy; depression; non trd ... See more keywords
Suicidality and Quality of Life in Treatment-Resistant Depression Patients in Latin America: Secondary Interim Analysis of the TRAL Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.812938
Abstract: Background A large proportion of patients with major depressive disorder (MDD) have treatment-resistant depression (TRD). The TRAL study examines the impact of TRD on suicidality and health-related quality of life (HRQoL) among MDD patients in… read more here.
Keywords: study; suicidality; trd patients; depression ... See more keywords
Changes in T-Cell Subpopulations and Cytokine Levels in Patients with Treatment-Resistant Depression—A Preliminary Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010479
Abstract: Although there is some evidence for the involvement of cytokines and T cells in the pathophysiology of treatment-resistant depression (TRD), the nature of this relationship is not entirely clear. Therefore, we compared T-cell subpopulations and… read more here.
Keywords: resistant depression; cell subpopulations; trd patients; depression ... See more keywords