Clinical efficacy of trauma-focused psychotherapies in treatment-resistant depression (TRD) in-patients: A randomized, controlled pilot-study
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2019.01.070
Abstract: In major depressive disorder (MDD) patients, life stress events represent a risk factor for a severe, early-onset, treatment-resistant and chronic endophenotype. Treatment-resistant depression (TRD) patients who have experienced traumatic events could benefit from evidence-based trauma-focused… read more here.
Keywords: trauma focused; treatment resistant; trd; focused psychotherapies ... See more keywords
Antidepressant Effect of Ketamine on Inflammation-Mediated Cytokine Dysregulation in Adults with Treatment-Resistant Depression: Rapid Systematic Review
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DOI: 10.1155/2022/1061274
Abstract: Background Major depressive disorder (MDD) and treatment-resistant depression (TRD) represent a global source of societal and health burden. To advise proper management of inflammation-related depression among TRD patients, it is important to identify therapeutic clinical… read more here.
Keywords: trd patients; ketamine; depression; antidepressant effect ... See more keywords
Ketamine Efficacy Across All Formulations in Treatment Resistant Depression in Adult Population: A Rapid Review
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DOI: 10.1192/bjo.2024.172
Abstract: Aims The primary aim of this rapid review was to evaluate the evidence base for the efficacy of ketamine across all formulations and routes of administrations in the treatment of adult patients with treatment resistant… read more here.
Keywords: treatment; review; across formulations; rapid review ... See more keywords
Age as a moderating factor of treatment resistance in depression
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DOI: 10.1192/j.eurpsy.2023.17
Abstract: Abstract Background Treatment-resistant depression (TRD) is an important clinical challenge and may present differently between age groups. Methods A total of 893 depressed patients recruited within the framework of the European research consortium “Group for… read more here.
Keywords: trd patients; depression; age; age moderating ... See more keywords
Abnormal Prefrontal Brain Activation During a Verbal Fluency Task in Treatment-Resistant Depression Using Near-Infrared Spectroscopy
Sign Up to like & getrecommendations! Published in 2023 at "Psychiatry Investigation"
DOI: 10.30773/pi.2021.0372
Abstract: Objective The study investigated cognitive performance and brain function between treatment-resistant depression (TRD) and non-TRD patients to find potential neurobiological markers associated with refractoriness in depression patients. Methods Fourteen TRD patients, 26 non-TRD patients and… read more here.
Keywords: trd patients; spectroscopy; depression; non trd ... See more keywords
Suicidality and Quality of Life in Treatment-Resistant Depression Patients in Latin America: Secondary Interim Analysis of the TRAL Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.812938
Abstract: Background A large proportion of patients with major depressive disorder (MDD) have treatment-resistant depression (TRD). The TRAL study examines the impact of TRD on suicidality and health-related quality of life (HRQoL) among MDD patients in… read more here.
Keywords: study; suicidality; trd patients; depression ... See more keywords
Changes in T-Cell Subpopulations and Cytokine Levels in Patients with Treatment-Resistant Depression—A Preliminary Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010479
Abstract: Although there is some evidence for the involvement of cytokines and T cells in the pathophysiology of treatment-resistant depression (TRD), the nature of this relationship is not entirely clear. Therefore, we compared T-cell subpopulations and… read more here.
Keywords: resistant depression; cell subpopulations; trd patients; depression ... See more keywords