Programmable macromolecule-based RNA-targeting therapies to treat human neurological disorders
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DOI: 10.1261/rna.079519.122
Abstract: Disruptions in RNA processing play critical roles in the pathogenesis of neurological diseases. In this Perspective, we discuss recent progress in the development of RNA-targeting therapeutic modalities. We focus on progress, limitations, and opportunities in… read more here.
Keywords: rna targeting; programmable macromolecule; neurological disorders; human neurological ... See more keywords
Mitochondrial Genome Editing to Treat Human Osteoarthritis—A Narrative Review
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DOI: 10.3390/ijms23031467
Abstract: Osteoarthritis (OA) is a severe, common chronic orthopaedic disorder characterised by a degradation of the articular cartilage with an incidence that increases over years. Despite the availability of various clinical options, none can stop the… read more here.
Keywords: genome editing; osteoarthritis; treat human; narrative review ... See more keywords