Reprogramming tumor stroma using an endogenous lipid lipoxin A4 to treat pancreatic cancer.
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DOI: 10.1016/j.canlet.2018.01.072
Abstract: Pancreatic stellate cells (PSCs) are the precursors of cancer-associated fibroblasts (CAFs), which potentiate pancreatic tumor growth and progression. In this study, we investigated whether Lipoxin A4 (LXA4), an endogenous bioactive lipid, can inhibit the differentiation… read more here.
Keywords: pancreatic cancer; hpscs; cancer; treat pancreatic ... See more keywords