Treat‐to‐target and sequencing therapies in Crohn's disease
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12336
Abstract: Abstract Crohn's disease (CD) is a chronic immune‐mediated inflammatory condition which can negatively impact a patient's quality of life. The traditional management strategy for CD has focused on symptomatic control, however, this approach fails to… read more here.
Keywords: disease; target sequencing; crohn disease; treat target ... See more keywords
Intravenous human immunoglobulin and/or methylprednisolone pulse therapies as a possible treat-to-target strategy in immune-mediated necrotizing myopathies
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology International"
DOI: 10.1007/s00296-019-04254-3
Abstract: To evaluate the relevance of immunoglobulin (IVIg) and/or methylprednisolone pulse therapies in immune-mediated necrotizing myopathy (IMNM). Secondarily, to analyze the muscle damage measured by late magnetic resonance images (MRI). This retrospective study included 13 patients… read more here.
Keywords: pulse therapies; methylprednisolone pulse; treat target; methylprednisolone ... See more keywords
Maneuvering Clinical Pathways for Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2019 at "Current Gastroenterology Reports"
DOI: 10.1007/s11894-019-0716-3
Abstract: Recent years have brought about several advances in the treatment of patients with ulcerative colitis (UC). Here, we discuss salient recommendations of recent treatment guidelines; review the efficacy, safety, and real-world data of vedolizumab and… read more here.
Keywords: risk; risk stratified; treat target; ulcerative colitis ... See more keywords
"It is good to have a target in mind": Qualitative views of patients and parents informing a treat to target clinical trial in JSLE.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab173
Abstract: OBJECTIVE We sought to explore patient and parental views on treatment targets, outcome measures and study designs being considered for a future juvenile-onset systemic lupus erythematosus (JSLE) treat to target (T2T) study. METHODS Topic guided,… read more here.
Keywords: treatment; patients parents; treat target; target ... See more keywords
Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac638
Abstract: OBJECTIVE To investigate associations between treat-to-target urate-lowering therapy (ULT) and hospitalisations for gout. METHODS Using linked Clinical Practice Research Datalink and NHS Digital Hospital Episode Statistics data, we described the incidence and timing of hospitalisations… read more here.
Keywords: risk hospitalisations; treat target; hospitalisations gout; target ... See more keywords
Treatment decisions in axial spondyloarthritis daily clinical practice are more than treat-to-target.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead155
Abstract: OBJECTIVE 'Treat-to-target principles' are advised for axial spondyloarthritis although a clear target is not yet defined and targets do not always reflect inflammation. Treat-to-target use and motives for treatment choices in clinics are unknown. Therefore,… read more here.
Keywords: disease activity; treatment; target; treat target ... See more keywords
Radiographic joint damage in early rheumatoid arthritis patients: comparing tocilizumab- and methotrexate-based treat-to-target strategies
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology"
DOI: 10.1093/rheumatology/kex386
Abstract: Objective To evaluate the progression of erosions and joint space narrowing (JSN) in feet and hands in the U-Act-Early trial. Methods In this trial, 317 newly diagnosed DMARD-naïve RA patients initiated randomly tocilizumab, or step-up… read more here.
Keywords: based treat; treat target; progression erosions; tocilizumab ... See more keywords
The role of ultrasound and magnetic resonance imaging for treat to target in rheumatoid arthritis and psoriatic arthritis.
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology"
DOI: 10.1093/rheumatology/kez397
Abstract: The treat-to-target (T2T) approach has revolutionized the way we treat patients with rheumatic and musculoskeletal diseases. Recent attention has focused on imaging techniques, in particular musculoskeletal ultrasound and MRI as a focus for T2T strategies.… read more here.
Keywords: treat; treat target; ultrasound magnetic; arthritis ... See more keywords
Conventional versus ultrasound treat to target: no difference in magnetic resonance imaging inflammation or joint damage over 2 years in early rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/kez674
Abstract: OBJECTIVE To investigate whether an ultrasound-guided treat-to-target strategy for early RA would lead to reduced MRI inflammation or less structural damage progression compared with a conventional treat-to-target strategy. METHODS A total of 230 DMARD-naïve early… read more here.
Keywords: strategy; inflammation; treat target; damage ... See more keywords
Go or no-go for treat-to-target in axial spondyloarthritis?
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000941
Abstract: Purpose of review For almost a decade, treat-to-target (T2T) has been advocated as a management strategy for axial spondyloarthritis (axSpA), despite a lack of trial evidence. Recently, the first and only published T2T trial in… read more here.
Keywords: axial spondyloarthritis; t2t; trial; treat target ... See more keywords
Limited uptake of ulcerative colitis “treat‐to‐target” recommendations in real‐world practice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.13923
Abstract: A “treat‐to‐target” approach has been proposed for ulcerative colitis (UC), with a target of combined clinical and endoscopic remission. The aim of the study was to evaluate the extent to which proposed targets are achieved… read more here.
Keywords: real world; ulcerative colitis; treat target; target ... See more keywords