Exosomes Derived from Senescent Endothelial Cells Contain Distinct Pro-angiogenic miRNAs and Proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular toxicology"
DOI: 10.1007/s12012-022-09740-y
Abstract: Exosomes from senescence cells play pivotal roles in endothelium dysfunction. We investigated the exosomal angiogenic cargo of endothelial cells (ECs) in a model of senescence in vitro. After inducing aging by H2O2, the expression of… read more here.
Keywords: expression; western blotting; mir 126; exosomes derived ... See more keywords
Phenotypic changes on central nervous system (CNS) tumor cell lines cultured in vitro 2D and 3D models and treated with cisplatin.
Sign Up to like & getrecommendations! Published in 2021 at "Acta histochemica"
DOI: 10.1016/j.acthis.2021.151768
Abstract: Despite aggressive therapy, most patients with brain tumors present disease relapse due to the cellular and molecular nature of these tumors. One of the models that best explains the heterogeneity observed in CNS tumors is… read more here.
Keywords: treated cells; cell lines; cisplatin treated; cisplatin ... See more keywords
Phenolics from Rubus fairholmianus induces cytotoxicity and apoptosis in human breast adenocarcinoma cells.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.08.005
Abstract: Herbal medicine is an important part of health care system in most of the countries. Rubus fairholmianus is an unexplored berry in folkloric medicine. In this study, we aimed to understand the importance of R. fairholmianus… read more here.
Keywords: medicine; treated cells; apoptosis; phenolics rubus ... See more keywords
P251 Testing HIV and HBV viral load in ffpe transplant biopsies with the cobas ®mpliprep/cobas®taqman®system
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.311
Abstract: Aim Determine if the COBAS® AmpliPrep/COBAS® TaqMan® System (COBAS® System) could be used to quantify viral loads of HIV and HBV in FFPE biopsies using as input sample purified RNA and DNA, respectively. Methods Cell… read more here.
Keywords: system; treated cells; dna; cobas ... See more keywords
DHCR24 overexpression modulates microglia polarization and inflammatory response via Akt/GSK3β signaling in Aβ25-35 treated BV-2 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118470
Abstract: Microglial phenotypic polarization, divided into pro-inflammatory "M1" phenotype and anti-inflammatory "M2" phenotype, played a crucial role in the pathogenesis of Alzheimer's disease (AD). Facilitating microglial polarization from M1 to M2 phenotype was shown to alleviate… read more here.
Keywords: phenotype; treated cells; polarization; inflammatory ... See more keywords
Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the JAK/STAT3 pathway in interleukin 6-treated PC-12 cells
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.10.001
Abstract: To understand the potential mechanisms involved in the beneficial effects of aspirin (ASA) in mood disorders, Alzheimer's (AD) and Parkinson's disease (PD), we investigated the effects of ASA on the expression of iron transport proteins… read more here.
Keywords: treated cells; stat3; expression inhibiting; expression ... See more keywords
Apoptosis-inducing effects of Terminalia phanerophlebia leaf extracts on human renal cells
Sign Up to like & getrecommendations! Published in 2021 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2021.03.009
Abstract: Abstract The study investigated the toxicogenic effects and molecular mechanisms of Terminalia phanerophlebia on human renal cells. The methylthiazol tetrazolium (MTT) assay was used to assess the cytotoxicity of a crude leaf extract of Terminalia… read more here.
Keywords: human renal; terminalia phanerophlebia; renal cells; apoptosis inducing ... See more keywords
Chemotherapy-treated cells go up in flames
Sign Up to like & getrecommendations! Published in 2017 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aan4289
Abstract: Apoptosis induced by chemotherapies can also trigger proinflammatory pyroptosis. Apoptosis induced by chemotherapies can also trigger proinflammatory pyroptosis. read more here.
Keywords: medicine; cells flames; chemotherapy treated; treated cells ... See more keywords
The Effect of A2E on the Ca2+-PKC Signaling Pathway in Human RPE Cells Exposed to Blue Light
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Ophthalmology"
DOI: 10.1155/2022/2233223
Abstract: Aims In a model of blue light-induced damage in N-retinylidene-N-retinylethanolamine (A2E)-loaded human retinal pigment epithelial (RPE) cells, we examined the effect of A2E on the calcium (Ca2+)-protein kinase C (PKC) signaling pathway. Methods Primary human… read more here.
Keywords: blue light; light a2e; treated cells; rpe cells ... See more keywords
Elucidating the mechanism underlying cognitive dysfunction by investigating the effects of CMF and MET treatment on hippocampal neurons.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202202_27981
Abstract: OBJECTIVE Chemotherapy causes long-term cognitive impairment in cancer survivors. A combination of cyclophosphamide (CYP), methotrexate (MTX), and 5-fluorouracil (5-FU) (i.e., CMF) is widely used for cancer treatment. Metformin (MET), an oral antidiabetic drug, confers protection… read more here.
Keywords: lipid peroxidation; met treated; treated cells; cmf ... See more keywords
Inactivation and Subsequent Growth Kinetics of Listeria monocytogenes After Various Mild Bactericidal Treatments
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.646735
Abstract: This study was carried out to investigate the effects of mild heat, lactic acid, benzalkonium chloride and nisin treatments on the inactivation, sublethal injury, and subsequent growth of Listeria monocytogenes. Results showed that the Bigelow… read more here.
Keywords: inactivation; growth; lag time; treated cells ... See more keywords