The role of TSPO PET in assessing neuroinflammation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurology"
DOI: 10.1007/s00415-017-8565-1
Abstract: Despite the advent of combined antiretroviral therapy and the consequent effective control of HIV RNA in both the serum and CSF, many HIV-positive patients still develop HIV-associated brain disease, including cognitive impairment. It has been… read more here.
Keywords: pet; role tspo; hiv patients; hiv ... See more keywords
Translocated microbiome composition determines immunological outcome in treated HIV infection
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.05.023
Abstract: The impact of the microbiome on HIV disease is widely acknowledged although the mechanisms downstream of fluctuations in microbial composition remain speculative. We detected rapid, dynamic changes in translocated microbial constituents during two years after… read more here.
Keywords: hiv infection; translocated microbiome; composition; treated hiv ... See more keywords
ApoA-I mimetics favorably impact cyclooxygenase 2 and bioactive lipids that may contribute to cardiometabolic syndrome in chronic treated HIV.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154888
Abstract: OBJECTIVE We investigated whether apolipoprotein A-I (apoA-I) mimetic peptides 4F and 6F can be a novel therapeutic strategy to reduce blood and gut bioactive lipids, proinflammatory effects of endotoxin (LPS) and aberrant activation of cyclooxygenase… read more here.
Keywords: syndrome chronic; cardiometabolic syndrome; bioactive lipids; treated hiv ... See more keywords
Fecal Bacterial Communities in treated HIV infected individuals on two antiretroviral regimens
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43741
Abstract: Intestinal microbiome changes that occur in HIV positive individuals on different antiretroviral therapy (ART) regimens are important to understand, as they are potentially linked with chronic inflammation and microbiome-linked comorbidities that occur at increased incidence… read more here.
Keywords: infected individuals; fecal bacterial; hiv; individuals two ... See more keywords
Plasma interleukin-6 (IL-6), angiopoietin-2, and C-reactive protein levels predict subsequent type 1 myocardial infarction in persons with treated HIV infection.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of acquired immune deficiency syndromes"
DOI: 10.1097/qai.0000000000003207
Abstract: BACKGROUND HIV infection leads to endothelial activation, promoting platelet adhesion and accelerating atherosclerosis. Our goal was to determine whether biomarkers of endothelial activation and hemostasis/thrombosis were elevated in people with treated HIV (PWH) before myocardial… read more here.
Keywords: predict subsequent; treated hiv; reactive protein; myocardial infarction ... See more keywords
HCV viraemia associates with NK cell activation and dysfunction in antiretroviral therapy‐treated HIV/HCV‐co‐infected subjects
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.12714
Abstract: The impact of hepatitis C virus (HCV) RNA levels on immune status in chronically HCV mono‐infected when compared to HIV/HCV co‐infected on antiretroviral therapy (ART) remains poorly understood. A total of 78 African American subjects… read more here.
Keywords: hiv hcv; cell activation; hcv; treated hiv ... See more keywords
Child treated for HIV in infancy has been healthy for nine years
Sign Up to like & getrecommendations! Published in 2017 at "British Medical Journal"
DOI: 10.1136/bmj.j3587
Abstract: A South African child who was infected with HIV at birth and given a short course of treatment at nine weeks old has remained healthy for the past nine years without further intervention, according to… read more here.
Keywords: child treated; nine years; healthy nine; infancy healthy ... See more keywords
Metabolic Syndrome and Combination Antiretroviral Therapy in HIV Patients in Periurban Hospital in Ghana: A Case-Control Study
Sign Up to like & getrecommendations! Published in 2023 at "AIDS Research and Treatment"
DOI: 10.1155/2023/1566001
Abstract: Background There is an increasing prevalence of cardiovascular diseases (CVDs) and risk factors in HIV patients as the levels of AIDS-related mortality and morbidity decrease. Metabolic syndrome (MetS) is the accumulation of various CVD risk… read more here.
Keywords: treated hiv; hiv; cart hiv; cart treated ... See more keywords
Global and regional brain hypometabolism on FDG-PET in treated HIV-infected individuals
Sign Up to like & getrecommendations! Published in 2018 at "Neurology"
DOI: 10.1212/wnl.0000000000006398
Abstract: Objective To quantitatively measure brain glucose metabolism in treated HIV-positive individuals with [18F]-labeled fluorodeoxyglucose (FDG) PET/CT. Methods We performed a cross-sectional comparison of FDG uptake in 47 treated HIV+ individuals, 10 age-matched controls (HIV−) sharing… read more here.
Keywords: hiv; fdg pet; hiv participants; treated hiv ... See more keywords
Peripheral blood HIV-1 DNA dynamics in antiretroviral-treated HIV/HCV co-infected patients receiving directly-acting antivirals
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0187095
Abstract: Background Aim was to determine the dynamics of peripheral blood mononuclear cells (PBMC)- associated total HIV-1 DNA in successfully ART-treated HIV/HCV co-infected patients receiving DAA treatment and to explore possible virological hypotheses underlying the phenomenon.… read more here.
Keywords: hiv dna; hiv hcv; hiv; treated hiv ... See more keywords
ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010160
Abstract: Novel therapeutic strategies are needed to attenuate increased systemic and gut inflammation that contribute to morbidity and mortality in chronic HIV infection despite potent antiretroviral therapy (ART). The goal of this study is to use… read more here.
Keywords: inflammation; treated hiv; gut; gut inflammation ... See more keywords