Time-Varying Outcomes With the Absorb Bioresorbable Vascular Scaffold During 5-Year Follow-up: A Systematic Meta-analysis and Individual Patient Data Pooled Study.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2019.4101
Abstract: Importance Bioresorbable scaffolds were designed to provide clinical benefits after their complete bioresorption. Prior studies demonstrated early risks with the Absorb polymeric bioresorbable vascular scaffold (BVS). Whether this risk profile changes over time during the… read more here.
Keywords: analysis; year follow; treated patients; bioresorbable vascular ... See more keywords
Investigation of drugs affecting hypertension in bevacizumab‐treated patients and examination of the impact on the therapeutic effect
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DOI: 10.1002/cam4.3587
Abstract: In patients treated with bevacizumab, hypertension may be a biomarker of therapeutic efficacy. However, it is not clear whether drugs that control blood pressure influence bevacizumab's efficacy. In this study, we investigated drugs that may… read more here.
Keywords: bevacizumab; impact therapeutic; hypertension bevacizumab; bevacizumab treated ... See more keywords
Secondary malignancies and survival of FCR‐treated patients with chronic lymphocytic leukemia in Central Europe
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5033
Abstract: This is the first large‐scale cross‐country analysis of patients with chronic lymphocytic leukemia (CLL) aimed to evaluate the incidence, types, and key prognostic factors of secondary malignancies, and to assess the impact on overall survival… read more here.
Keywords: patients chronic; lymphocytic leukemia; secondary malignancies; treated patients ... See more keywords
Assessment of omega‐3 carboxylic acids in statin‐treated patients with high levels of triglycerides and low levels of high‐density lipoprotein cholesterol: Rationale and design of the STRENGTH trial
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DOI: 10.1002/clc.23055
Abstract: It is uncertain whether omega‐3 fatty acids are beneficial in statin‐treated patients. Epanova is a mix of omega‐3 free fatty acids, not requiring co‐ingestion with food, which can lower triglycerides by up to 31%. STRENGTH… read more here.
Keywords: strength; risk; trial; statin ... See more keywords
Systemic corticosteroids for the treatment of acute episodes of rhabdomyolysis in lipin-1-deficient patients.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of inherited metabolic disease"
DOI: 10.1002/jimd.12592
Abstract: OBJECTIVES Mutations in the LPIN1 gene constitute a major cause of severe rhabdomyolysis (RM). The TLR9 activation prompted us to treat patients with corticosteroids in acute conditions. METHODS In patients with LPIN1 mutations, RM and… read more here.
Keywords: rhabdomyolysis; systemic corticosteroids; corticosteroid treated; treated corticosteroids ... See more keywords
Real‐life impact of tenofovir disoproxil fumarate and entecavir therapy on lipid profile, glucose, and uric acid in chronic hepatitis B patients
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DOI: 10.1002/jmv.27977
Abstract: The impact of long‐term nucleos(t)ide analogs treatment on host metabolism is a concern. Hence, we conducted this study to compare the effect of entecavir (ETV) and tenofovir disoproxil fumarate (TDF) on metabolic parameters among chronic… read more here.
Keywords: real life; chronic hepatitis; tenofovir disoproxil; treated patients ... See more keywords
Differential Benefit of Collaterals for Stroke Patients Treated with Thrombolysis or Supportive Care
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-019-00815-y
Abstract: Leptomeningeal collaterals can slow down infarction growth; however, despite good collaterals in the DAWN and DEFUSE 3 trials, outcomes were devastating if reperfusion was not attempted. The aim of this study was to compare the… read more here.
Keywords: ivt treated; supportive care; ivt; stroke patients ... See more keywords
Surgical outcomes of patients treated with ustekinumab vs. vedolizumab in inflammatory bowel disease: a matched case analysis
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DOI: 10.1007/s00384-018-3212-6
Abstract: AimThe association between preoperative use of monoclonal antibodies in inflammatory bowel disease (IBD) patients and postoperative complications is controversial, especially for the latest approved biologics, ustekinumab and vedolizumab, where data is limited. We hypothesized that… read more here.
Keywords: ustekinumab vedolizumab; inflammatory bowel; analysis; disease ... See more keywords
Brolucizumab for pre-treated patients with choroidal neovascularization and signs of tachyphylaxis to aflibercept and bevacizumab
Sign Up to like & getrecommendations! Published in 2022 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-022-05634-5
Abstract: Treatment of choroidal neovascularization due to age-related macular degeneration is a challenging topic since an increasing number of patients show reduced morphological response to conventional treatment with intravitreal injections. The present study tested the hypothesis… read more here.
Keywords: brolucizumab; pre treated; treated patients; treatment ... See more keywords
A pilot study on the melatonin treatment in patients with early septic shock: results of a single-center randomized controlled trial
Sign Up to like & getrecommendations! Published in 2021 at "Irish Journal of Medical Science"
DOI: 10.1007/s11845-021-02758-1
Abstract: We assessed the potential impact of a high dose of melatonin treatment in patients with early septic shock. Forty patients with early septic shock were randomly allocated to the melatonin or placebo groups. Besides standard-of-care… read more here.
Keywords: patients early; septic shock; treatment; group ... See more keywords
Clinical and Economic Burden of Patients with Chronic Hepatitis C with Versus Without Antiviral Treatment in Japan: An Observational Cohort Study Using Hospital Claims Data
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DOI: 10.1007/s40121-019-0234-5
Abstract: IntroductionJapan has one of the highest prevalence rate of chronic hepatitis C (CHC) in the industrialized world. However, the burden of CHC treatment is poorly understood. Thus, the healthcare resource utilization and costs of treated… read more here.
Keywords: treatment; untreated patients; cohort; chronic hepatitis ... See more keywords