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Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.1170
Abstract: Upadacitinib (UPA), an oral Janus kinase inhibitor, and ustekinumab (UST), a parenteral IL 12/23 antagonist, are effective treatments for moderately to severely active Crohn’s Disease (CD). In the absence of head-to-head data, a placebo (PBO)-anchored…
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Keywords:
moderately severely;
upa ust;
response;
treated pts ... See more keywords
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Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-5600
Abstract: Introduction JAK inhibition is the basis of treatment for most patients (pts) with myelofibrosis (MF). Early JAK inhibitors (ruxolitinib (RUX) and fedratinib) result in myelosuppression that often exacerbates disease-related anemia and thrombocytopenia. The FDA-approval of…
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Keywords:
mom;
mom treated;
pac treated;
treated pts ... See more keywords
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Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.4012
Abstract: 4012 Background: NIVO monotherapy (mono) is approved for sorafenib (SOR)-treated pts with HCC based on data from CheckMate 040 (NCT01658878), which reported an objective response rate (ORR) of 14% and median overall survival (mOS) of…
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Keywords:
ipi;
treated pts;
nivo ipi;
checkmate 040 ... See more keywords
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Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.7_suppl.614
Abstract: 614 Background: Axitinib (axi) is approved for 2nd-line treatment of aRCC. In AXIS trial, median progression-free survival (PFS) was significantly longer in axi- vs sorafenib (sor)-treated pts (hazard ratio [HR] 0.67, 95% CI 0.54–0.81, P
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Keywords:
axi sor;
axi;
treated pts;
angiogenic immunomodulatory ... See more keywords