Clinical Outcomes in COVID‐19 Patients Treated with Tocilizumab: An Individual Patient Data Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26038
Abstract: Current evidence suggests an important role of the interleukin‐6 (IL‐6) pathway in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐related cytokine release storm in severely ill coronavirus disease 2019 (COVID‐19) patients. Inhibition of the IL‐6 pathway… read more here.
Keywords: covid patients; patients treated; clinical outcomes; outcomes covid ... See more keywords
Pulmonary vascular improvement in severe COVID-19 patients treated with tocilizumab
Sign Up to like & getrecommendations! Published in 2020 at "Immunology Letters"
DOI: 10.1016/j.imlet.2020.10.009
Abstract: As of October 2020 management of Coronavirus disease 2019 (COVID-19) is based on supportive care and off-label or compassionate-use therapies. On March 2020 tocilizumab - an anti-IL-6 receptor monoclonal antibody - was suggested as immunomodulatory… read more here.
Keywords: covid patients; patients treated; pulmonary vascular; covid ... See more keywords
Clinical course of severe COVID19 treated with tocilizumab and antivirals post‐allogeneic stem cell transplant with extensive chronic GVHD
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DOI: 10.1111/tid.13576
Abstract: Recipients of allogeneic hematopoietic stem cell transplantation (allo‐HSCT) are an immunocompromised group who are likely to develop severe complications and mortality because of coronavirus disease 2019 (COVID‐19). We report here a 61‐year‐old male patient of… read more here.
Keywords: stem cell; severe covid19; treated tocilizumab;
Analysis of IL-6 measurement in patients with GCA treated with tocilizumab should consider concomitant treatment with prednisone
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-215697
Abstract: We read with great interest the letter published by Berger et al in which the authors showed that relapse-free survival for giant cell arteritis (GCA) treated with tocilizumab (TCZ) was longer in patients with an… read more here.
Keywords: patients gca; gca treated; analysis measurement; measurement patients ... See more keywords
Necrotising soft tissue infection without systemic toxicity in a patient with rheumatoid arthritis treated with tocilizumab
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DOI: 10.1136/bcr-2017-222826
Abstract: A Japanese woman aged 76 years with rheumatoid arthritis treated with prednisolone and tocilizumab presented with a 2-day history of redness and pain in her right thigh. She was hospitalised with a primary diagnosis of… read more here.
Keywords: necrotising soft; soft tissue; tissue infection; arthritis treated ... See more keywords
Predictive factors of clinical outcomes in patients with COVID-19 treated with tocilizumab: A monocentric retrospective analysis
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DOI: 10.1371/journal.pone.0262908
Abstract: Objective The aim of this retrospective observational study is to analyse clinical, serological and radiological predictors of outcome in patients with COVID-19 pneumonia treated with tocilizumab, providing clinical guidance to its use in real-life. Method… read more here.
Keywords: predictive factors; analysis; clinical outcomes; factors clinical ... See more keywords
TAFRO Syndrome with Disseminated Intravascular Coagulation Successfully Treated with Tocilizumab and Recombinant Thrombomodulin
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine"
DOI: 10.2169/internalmedicine.9484-17
Abstract: TAFRO syndrome is a systemic inflammatory disorder that is characterized by thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly. Although thrombocytopenia is one of the major features of TAFRO syndrome, complications of disseminated intravascular coagulation (DIC)… read more here.
Keywords: disseminated intravascular; intravascular coagulation; successfully treated; recombinant thrombomodulin ... See more keywords