Novel AT2R Antagonists for Treating Chronic Pain.
Sign Up to like & getrecommendations! Published in 2024 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.4c00046
Abstract: Provided herein are novel AT2R antagonists, pharmaceutical compositions, use of such compounds in treating chronic pain, and processes for preparing such compounds. read more here.
Keywords: treating chronic; chronic pain; at2r antagonists; antagonists treating ... See more keywords
Efficacy and safety of Xinnaoning capsule in treating chronic stable angina (qi stagnation and blood stasis syndrome)
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000016539
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: efficacy safety; safety xinnaoning; xinnaoning capsule; chronic stable ... See more keywords
Treating chronic hepatitis E: when is enough enough?
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-223592
Abstract: We present a 38-year-old white British man who was taking long-term immunosuppressive medication following kidney transplantation. On routine review, he was noted to have an isolated and asymptomatic rise in alanine aminotransferase. After thorough investigation,… read more here.
Keywords: hepatitis; enough enough; treatment; hepatitis enough ... See more keywords
Multidisciplinary Approach to Treating Chronic Pain in Patients with Ehlers–Danlos Syndrome: Critically Appraised Topic
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pain Research"
DOI: 10.2147/jpr.s377790
Abstract: Abstract The Ehlers–Danlos syndromes (EDS) are a group of 13 related connective tissue disorders with a combined prevalence of 1 in 5000 people, with the most common noted as hypermobile EDS (hEDS). The EDS genetic… read more here.
Keywords: multidisciplinary approach; chronic pain; pain; ehlers danlos ... See more keywords
Targeting Serotonin1A Receptors for Treating Chronic Pain and Depression
Sign Up to like & getrecommendations! Published in 2019 at "Current Neuropharmacology"
DOI: 10.2174/1570159x17666190811161807
Abstract: The association of chronic pain with depression is becoming increasingly recognized. Treating both the conditions together is essential for an effective treatment outcome. In this regard, it is important to identify a shared mechanism involved… read more here.
Keywords: pain depression; pain; targeting serotonin1a; chronic pain ... See more keywords
Current research progress of local drug delivery systems based on biodegradable polymers in treating chronic osteomyelitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1042128
Abstract: Chronic osteomyelitis is one of the most challenging diseases in orthopedic treatment. It is usually treated with intravenous antibiotics and debridement in clinical practice, which also brings systemic drug side effects and bone defects. The… read more here.
Keywords: osteomyelitis; local drug; treating chronic; delivery ... See more keywords
Vitamin D: A Potential Star for Treating Chronic Pancreatitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.902639
Abstract: Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the pancreas. The incidence of CP is increasing worldwide but the effective therapies are lacking. Hence, it is necessary to identify economical and effective… read more here.
Keywords: potential star; vitamin potential; chronic pancreatitis; star treating ... See more keywords
Targeting GRK5 for Treating Chronic Degenerative Diseases
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041920
Abstract: G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors and they are responsible for the transduction of extracellular signals, regulating almost all aspects of mammalian physiology. These receptors are specifically regulated by a… read more here.
Keywords: degenerative diseases; targeting grk5; chronic degenerative; grk5 treating ... See more keywords
Comparison of Spinal Cord Stimulation Waveforms for Treating Chronic Low Back Pain: Systematic Review and Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Pain physician"
DOI: 10.36076/ppj.2020/23/451
Abstract: BACKGROUND The treatment of chronic refractory low back pain (LBP) is challenging. Conservative and pharmacologic options have demonstrated limited efficacy. Spinal cord stimulation (SCS) has been shown to be effective in reducing chronic LBP in… read more here.
Keywords: meta analysis; pain; chronic lbp; stimulation ... See more keywords
Therapeutic delivery of nucleic acids for skin wound healing.
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic delivery"
DOI: 10.4155/tde-2022-0003
Abstract: Though wound care has advanced, treating chronic wounds remains a challenge and there are many clinical issues that must be addressed. Gene therapy is a recent approach to treating chronic wounds that remains in its… read more here.
Keywords: therapeutic delivery; nucleic acids; delivery nucleic; chronic wounds ... See more keywords
The alchemy of precision and innovation: treating chronic airway inflammatory conditions in 2025.
Sign Up to like & getrecommendations! Published in 2025 at "Rhinology"
DOI: 10.4193/rhin25.902
Abstract: Chronic inflammatory processes of the upper and lower airways can represent a nightmare for both the treating physician as well as suffering patients. The advent of biologicals and use of personalized medicine has revolutionized its… read more here.
Keywords: innovation treating; treating chronic; alchemy precision; airway inflammatory ... See more keywords