Skull defect increases the tumor treating fields strength without detrimental thermogenic effect: A computational simulating research
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5037
Abstract: Tumor treating fields (TTFields) is an FDA‐approved adjuvant therapy for glioblastoma. The distribution of an applied electric field has been shown to be governed by distinct tissue structures and electrical conductivity. Of all the tissues… read more here.
Keywords: skull defect; defect increases; treating fields; tumor treating ... See more keywords
Synergistic inhibition of glioma cell proliferation by Withaferin A and tumor treating fields
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2534-5
Abstract: Glioblastoma (GBM) is the most aggressive and lethal form of brain cancer. Standard therapies are non-specific and often of limited effectiveness; thus, efforts are underway to uncover novel, unorthodox therapies against GBM. In previous studies,… read more here.
Keywords: proliferation; treating fields; glioma cell; cell ... See more keywords
Association between conflict of interest and published position on tumor-treating fields for the treatment of glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cancer Policy"
DOI: 10.1016/j.jcpo.2019.100189
Abstract: Abstract Objective To investigate a possible association between authors’ financial conflict-of-interest and published position on the clinical application of a medical device utilizing tumor-treating fields (TTF) for the treatment of Glioblastoma. Methods We searched Google… read more here.
Keywords: conflict; glioblastoma; treating fields; conflict interest ... See more keywords
Tumor Treating Fields Technology: Alternating Electric Field Therapy for the Treatment of Solid Tumors.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in oncology nursing"
DOI: 10.1016/j.soncn.2018.03.005
Abstract: OBJECTIVE To provide an overview of Tumor Treating Fields (TTFields) and the Optune device in the treatment of glioblastoma multiforme as well as discuss the evolution of TTFields technology for the treatment of different tumor… read more here.
Keywords: solid tumors; treatment; technology; treating fields ... See more keywords
Tumour treating fields therapy for glioblastoma: current advances and future directions
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-01136-5
Abstract: Glioblastoma multiforme (GBM) is the most common primary brain tumour in adults and continues to portend poor survival, despite multimodal treatment using surgery and chemoradiotherapy. The addition of tumour-treating fields (TTFields)—an approach in which alternating… read more here.
Keywords: glioblastoma current; therapy glioblastoma; tumour treating; fields therapy ... See more keywords
Effects of tumor treating fields (TTFields) on glioblastoma cells are augmented by mitotic checkpoint inhibition
Sign Up to like & getrecommendations! Published in 2018 at "Cell Death Discovery"
DOI: 10.1038/s41420-018-0079-9
Abstract: Tumor treating fields (TTFields) are approved for glioblastoma (GBM) therapy. TTFields disrupt cell division by inhibiting spindle fiber formation. Spindle assembly checkpoint (SAC) inhibition combined with antimitotic drugs synergistically decreases glioma cell growth in cell… read more here.
Keywords: treatment; inhibition; fields ttfields; treating fields ... See more keywords
Tumor treating fields: a comprehensive overview of the underlying molecular mechanism
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2017283
Abstract: ABSTRACT Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-intensity, medium-frequency electric fields on tumor cells. TTFields’ effectiveness and safety have been demonstrated clinically and in the real world for treating glioblastoma,… read more here.
Keywords: tumor; fields comprehensive; comprehensive overview; tumor treating ... See more keywords
End-to-end workflow for finite element analysis of tumor treating fields in glioblastomas.
Sign Up to like & getrecommendations! Published in 2017 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/aa87f3
Abstract: Tumor Treating Fields (TTFields) therapy is an approved modality of treatment for glioblastoma. Patient anatomy-based finite element analysis (FEA) has the potential to reveal not only how these fields affect tumor control but also how… read more here.
Keywords: finite element; tumor; analysis; element analysis ... See more keywords
Safety and efficacy of tumour-treating fields (TTFields) therapy for newly diagnosed glioblastoma in Japanese patients using the Novo-TTF System: a prospective post-approval study
Sign Up to like & getrecommendations! Published in 2023 at "Japanese Journal of Clinical Oncology"
DOI: 10.1093/jjco/hyad001
Abstract: Abstract Background Tumour-treating fields therapy is a locoregional, anti-cancer treatment. Efficacy and safety of tumour-treating fields therapy in adults with newly diagnosed glioblastoma were demonstrated in the pivotal phase 3 EF-14 study (NCT00916409). Here, we… read more here.
Keywords: survival; diagnosed glioblastoma; newly diagnosed; treating fields ... See more keywords
IMMU-42. DUAL ACTIVATION OF THE cGAS-STING PATHWAY AND AIM2-INDUCED PYROPTOSIS BY TUMOR-TREATING FIELDS PRODUCES ANTI-TUMOR IMMUNITY IN GLIOBLASTOMA
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.472
Abstract: Tumor Treating Fields (TTFields) was approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed Glioblastoma (GBM) patients and resulted in a significant improvement in overall survival. TTFields are low-intensity alternating electric fields that are… read more here.
Keywords: tumor; pyroptosis; gbm; activation ... See more keywords
P14.92 Combination of Tumor Treating Fields and CCNU chemotherapy as valuable option for the treatment of unresectable progressive glioblastoma: A case presentation
Sign Up to like & getrecommendations! Published in 2021 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noab180.193
Abstract: Tumor Treating Fields (TTFields) are low intensity (1–3 V/cm) alternating electric fields with an intermediate frequency of 100–300 kHz. TTFields in addition to temozolomide (TMZ) after radiochemotherapy according to Stupp significantly increased progression-free survival (PFS),… read more here.
Keywords: combination; tumor; treating fields; ccnu chemotherapy ... See more keywords