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Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.120875
Abstract: Inflammatory disease (ID) is an umbrella term encompassing all illnesses involving chronic inflammation as the central manifestation of pathogenesis. These include, inflammatory bowel diseases, hepatitis, pulmonary disorders, atherosclerosis, myocardial infarction, pancreatitis, arthritis, periodontitis, psoriasis. The…
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Keywords:
treating inflammatory;
inflammatory diseases;
immunomodulatory nanosystems;
imns ... See more keywords
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Published in 2023 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.3c00139
Abstract: Provided herein are novel imidazotriazine derivatives used as IL-17 modulators, their pharmaceutical compositions, the use of such compounds in treating inflammatory and autoimmune disorders, and processes for preparing such compounds.
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Keywords:
inflammatory autoimmune;
treating inflammatory;
novel imidazotriazine;
imidazotriazine derivatives ... See more keywords
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Published in 2024 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.4c00044
Abstract: Provided herein are novel pyrrolidinone derivatives as NIK inhibitors, pharmaceutical compositions, use of such compounds in treating inflammatory and autoimmune diseases, and processes for preparing such compounds.
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Keywords:
pyrrolidinone derivatives;
inflammatory autoimmune;
nik inhibitors;
autoimmune diseases ... See more keywords
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Published in 2025 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.5c00679
Abstract: Provided herein are novel imidazopyridazine compounds as IL-17 inhibitors, pharmaceutical compositions, use of such compounds in treating inflammatory diseases, and processes for preparing such compounds.
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Keywords:
novel imidazopyridazine;
imidazopyridazine compounds;
treating inflammatory;
compounds inhibitors ... See more keywords