Design, synthesis, and biological evaluation of novel catecholopyrimidine based PDE4 inhibitor for the treatment of atopic dermatitis.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.12.069
Abstract: Selective inhibition of phosphodiesterase (PDE) 4B favorably suppresses the synthesis of inflammatory cytokines and subsequently arrest the development of atopic dermatitis via modulating the intracellular cAMP levels. Considering the side effects of corticosteroids, selective PDE4… read more here.
Keywords: atopic dermatitis; dermatitis; treatment atopic; synthesis ... See more keywords
Successful response of upadacitinib in the treatment of atopic dermatitis lesions involving sensitive and visible areas resistant to dupilumab.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llad040
Abstract: Beneficial effects of upadacitinib in the treatment of atopic dermatitis (AD) patients who resulted unresponsive to dupilumab therapy have been described. AD lesions resistant to dupilumab and localized in sensitive and visible areas showed a… read more here.
Keywords: upadacitinib treatment; treatment atopic; sensitive visible; visible areas ... See more keywords
What's new in the treatment of atopic dermatitis?
Sign Up to like & getrecommendations! Published in 2019 at "Dermatologic Therapy"
DOI: 10.1111/dth.12787
Abstract: Atopic dermatitis (AD) is a pruritic, chronic and inflammatory skin disease, with an usual onset in the pediatric age. Several drugs are used in the treatment of this skin disease. Drugs as steroid, calcineurin inhibitors,… read more here.
Keywords: treatment; disease; atopic dermatitis; new treatment ... See more keywords
Methotrexate in atopic eczema. Comments to: Consensus‐based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.15386
Abstract: The recent European guidelines for the treatment of atopic eczema (AE) are a thorough overview of therapeutic opportunities for AE.1 Among the systemic treatments, we propose to bring further insights on methotrexate (MTX) use in… read more here.
Keywords: atopic eczema; guidelines treatment; atopic; european guidelines ... See more keywords
Mapping exercise and status update of eight established registries within the TREatment of ATopic eczema Registry Taskforce
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18566
Abstract: The TREatment of ATopic eczema (TREAT) Registry Taskforce is a collaborative international network of registries collecting data of atopic eczema (AE) patients receiving systemic and phototherapy with the common goal to provide long‐term real‐world data… read more here.
Keywords: registry taskforce; treatment atopic; atopic eczema;
Review of Tralokinumab in the Treatment of Atopic Dermatitis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Pharmacotherapy"
DOI: 10.1177/10600280221105686
Abstract: Objective To review pharmacokinetics, efficacy, and safety of tralokinumab in treatment of atopic dermatitis (AD). Data Sources Literature review was conducted using MEDLINE (PubMed), EMBASE, and ClinicalTrials.gov for articles published between January 2010 and May… read more here.
Keywords: tralokinumab; review; treatment atopic; atopic dermatitis ... See more keywords
Treatment of Atopic Dermatitis with Baricitinib: First Real-life Experience
Sign Up to like & getrecommendations! Published in 2022 at "Acta Dermato-Venereologica"
DOI: 10.2340/actadv.v102.1088
Abstract: Abstract is missing (Short communication) read more here.
Keywords: dermatitis baricitinib; real life; baricitinib first; treatment atopic ... See more keywords
OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis—Focus on Rocatinlimab and Amlitelimab
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122753
Abstract: Despite the recent emergence of targeted therapeutic options, there are still unmet needs concerning moderate-to-severe atopic dermatitis treatment. This review aims to discuss the OX40-OX40L pathway as a therapeutic target for the treatment of atopic… read more here.
Keywords: atopic dermatitis; ox40 ox40l; treatment; treatment atopic ... See more keywords