Acidity-Activatable Nanoparticles with Glucose Oxidase-Enhanced Photoacoustic Imaging and Photothermal Effect, and Macrophage-Related Immunomodulation for Synergistic Treatment of Biofilm Infection.
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DOI: 10.1002/smll.202204377
Abstract: The pH-responsive theragnostics exhibit great potential for precision diagnosis and treatment of diseases. Herein, acidity-activatable nanoparticles of GB@P based on glucose oxidase (GO) and polyaniline are developed for treatment of biofilm infection. Catalyzed by GO,… read more here.
Keywords: biofilm; treatment biofilm; biofilm infection; effect ... See more keywords
Targeting Multidrug-Recalcitrant Pseudomonas aeruginosa Biofilms: Combined-Enzyme Treatment Enhances Antibiotic Efficacy
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DOI: 10.1128/aac.01358-22
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen that forms biofilms during infection, resulting in recalcitrance to antibiotic treatment. Biofilm inhibition is a promising research direction for the treatment of biofilm-associated infections. ABSTRACT Pseudomonas aeruginosa is an… read more here.
Keywords: pseudomonas aeruginosa; targeting multidrug; treatment biofilm; combined enzyme ... See more keywords