New Developments in the Use of Atypical Antipsychotics in the Treatment of Bipolar Disorder: a Systematic Review of Recent Randomized Controlled Trials
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DOI: 10.1007/s11920-021-01252-w
Abstract: Atypical antipsychotics are increasingly used in the treatment of bipolar disorder (BD). This systematic review provides an overview of recently published randomized controlled trials (RCTs) on the efficacy and safety of atypical antipsychotics in BD.… read more here.
Keywords: atypical antipsychotics; treatment bipolar; treatment; systematic review ... See more keywords
A Review of Asenapine in the Treatment of Bipolar Disorder
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DOI: 10.1007/s40261-017-0592-2
Abstract: Bipolar disorder places a significant burden on the affected individuals, their family, healthcare systems and the overall economy. More treatment options are needed, especially those with better efficacy and tolerability. Asenapine is a second-generation antipsychotic… read more here.
Keywords: treatment bipolar; disorder; bipolar disorder; review asenapine ... See more keywords
A gene co-expression module implicating the mitochondrial electron transport chain is associated with long-term response to lithium treatment in bipolar affective disorder
Sign Up to like & getrecommendations! Published in 2018 at "Translational Psychiatry"
DOI: 10.1038/s41398-018-0237-0
Abstract: Lithium is the first-line treatment for bipolar affective disorder (BPAD) but two-thirds of patients respond only partially or not at all. The reasons for this high variability in lithium response are not well understood. Transcriptome-wide… read more here.
Keywords: response; treatment bipolar; module; bipolar affective ... See more keywords
Cariprazine for the treatment of bipolar depression: a review
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2019.1580571
Abstract: ABSTRACT Introduction: Depressive symptoms and episodes dominate the course of bipolar disorder. The morbidity of bipolar disorder is disproportionately mediated by depressive symptoms; economic costs of bipolar disorder are also disproportionately due to unremitting depressive… read more here.
Keywords: depression; treatment bipolar; bipolar depression; bipolar disorder ... See more keywords
Effectiveness and safety of monoamine oxidase inhibitor treatment for bipolar depression versus unipolar depression: An exploratory case cohort study
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DOI: 10.1111/acps.13518
Abstract: Patients with bipolar disorder spend most of their clinical lifetime in the depressive phase of their illness. However, antidepressants are discouraged in the treatment of bipolar depression due to concerns over manic induction and drug… read more here.
Keywords: versus unipolar; bipolar depression; depression; unipolar depression ... See more keywords
What is the optimal serum level for lithium in the maintenance treatment of bipolar disorder? A systematic review and recommendations from the ISBD/IGSLI Task Force on treatment with lithium
Sign Up to like & getrecommendations! Published in 2019 at "Bipolar Disorders"
DOI: 10.1111/bdi.12805
Abstract: To systematically review the existing trials on optimal serum levels for lithium for maintenance treatment of bipolar disorder and to develop clinical recommendations. read more here.
Keywords: maintenance treatment; treatment bipolar; treatment; optimal serum ... See more keywords
Commentary: Lithium treatment for bipolar disorder
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DOI: 10.1111/bdi.12997
Abstract: Introduction of lithium carbonate to treat manic excitement in 1949 by John Cade in Melbourne opened a new, revolutionary era in psychiatry with the first clinically effective pharmacological treatment for a major psychiatric disorder. By… read more here.
Keywords: treatment bipolar; treatment; commentary lithium; lithium ... See more keywords
Aripiprazole in the treatment of bipolar disorder due to traumatic brain injury: A case description
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DOI: 10.1111/bdi.13038
Abstract: A 29-year-old man is involuntarily transferred by the police to the Psychiatric Emergency Room. He exhibits intense irritability, aggressiveness, disorganized behavior and reiterated breaking of civic standards. According to the patient's family, behavioral alterations began… read more here.
Keywords: traumatic brain; treatment bipolar; due traumatic; aripiprazole treatment ... See more keywords
Long‐term treatment of bipolar disorder type I: A systematic and critical review of clinical guidelines with derived practice algorithms
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DOI: 10.1111/bdi.13040
Abstract: This systematic review aimed at providing a critical, comprehensive synthesis of international guidelines’ recommendations on the long‐term treatment of bipolar disorder type I (BD‐I). read more here.
Keywords: treatment bipolar; long term; term treatment; review ... See more keywords
Pharmacological treatment of bipolar disorder and risk of diabetes mellitus: A nationwide study of 30,451 patients.
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DOI: 10.1111/bdi.13308
Abstract: OBJECTIVE While treatment with antipsychotics and antiepileptics have been associated with an increased risk of DM, lithium may have the opposite effect via inhibition of glycogen synthase kinase-3. The aim of this study was to… read more here.
Keywords: bipolar disorder; risk; lithium; treatment bipolar ... See more keywords
Cariprazine for the Treatment of Bipolar Disorder
Sign Up to like & getrecommendations! Published in 2017 at "Perspectives in Psychiatric Care"
DOI: 10.1111/ppc.12150
Abstract: PURPOSE To review the data regarding a new antipsychotic, cariprazine. CONCLUSIONS Cariprazine is a dopamine D3, D2 partial agonist, with greater affinity to D3. It has been examined for schizophrenia, bipolar mania, bipolar depression, and… read more here.
Keywords: depression; treatment bipolar; treatment; cariprazine treatment ... See more keywords