Papaverine, a promising therapeutic agent for the treatment of COVID‐19 patients with underlying cardiovascular diseases (CVDs)
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DOI: 10.1002/ddr.21961
Abstract: The causative agent of coronavirus disease‐2019 (COVID‐19), severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), enters the host cells via an angiotensin‐converting enzyme 2 (ACE2)‐mediated endocytosis‐dependent manner. Because ACE2 is highly expressed in the heart, SARS‐CoV‐2… read more here.
Keywords: patients underlying; covid; treatment covid; treatment ... See more keywords
Antiandrogens for the treatment of COVID‐19 patients: A meta‐analysis of randomized controlled trials
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DOI: 10.1002/jmv.28740
Abstract: Antiandrogens may carry a potential benefit as a therapeutic agent against COVID‐19. However, studies have been yielding mixed results, thus hindering any objective recommendations. This necessitates a quantitative synthesis of data to quantify the benefits… read more here.
Keywords: antiandrogens treatment; randomized controlled; controlled trials; covid ... See more keywords
Nanoformulated Remdesivir with Extremely Low Content of Poly(2‐oxazoline)‐Based Stabilizer for Aerosol Treatment of COVID‐19
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DOI: 10.1002/mabi.202200056
Abstract: The rise of the novel virus SARS-CoV2 which causes the disease known as COVID-19 has led to a global pandemic claiming millions of lives. With no clinically approved treatment for COVID-19, physicians initially struggled to… read more here.
Keywords: nanoformulated remdesivir; covid; poly oxazoline; treatment covid ... See more keywords
Paxlovid: antiviral combination for the treatment of COVID‐19
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DOI: 10.1002/psb.1979
Abstract: Paxlovid (nirmatrelvir/ritonavir) is an oral antiviral combination for the treatment of COVID‐19 in adults at risk of progression to severe disease. This article summarises its indications, interactions and efficacy. read more here.
Keywords: treatment covid; antiviral combination; combination treatment;
Exploration of molecular targets and mechanisms of Chinese medicinal formula Acacia Catechu ‐Scutellariae Radix in the treatment of COVID‐19 by a systems pharmacology strategy
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DOI: 10.1002/ptr.7554
Abstract: Coronavirus disease 2019 (COVID‐19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). In China, the Acacia catechu (AC)‐Scutellariae Radix (SR) formula has been widely used for pulmonary infection in clinical practice for several… read more here.
Keywords: pharmacology; acacia catechu; treatment covid; formula ... See more keywords
Review on molnupiravir as a promising oral drug for the treatment of COVID-19
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DOI: 10.1007/s00044-021-02841-3
Abstract: During the COVID-19 pandemic, various drug candidates have been developed, molnupiravir (MK-4482 and EIDD-2801), which is a new orally anti-viral agent under development for the treatment of COVID-19, is under study in the final stage… read more here.
Keywords: chemistry; molnupiravir; treatment covid; drug ... See more keywords
Investigational antiviral drugs for the treatment of COVID-19 patients.
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DOI: 10.1007/s00705-022-05368-z
Abstract: In the current pandemic of coronavirus disease 2019 (COVID-19), antiviral drugs are at the center of attention because of their critical role against severe acute respiratory disease syndrome coronavirus 2 (SARS-CoV-2). In addition to designing… read more here.
Keywords: investigational antiviral; drugs treatment; antiviral drugs; covid ... See more keywords
Hydroxychloroquine and azithromycin as a treatment of COVID-19
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DOI: 10.1007/s11739-020-02388-y
Abstract: Since the emerging of the new coronavirus disease (COVID19) with its staggering worldwide morbidity and mortality, the scientific community has been placed under extraordinary pressure to find safe and effective treatments, pending the availability of… read more here.
Keywords: treatment covid; azithromycin treatment; hydroxychloroquine; medicine ... See more keywords
Potential metal-related strategies for prevention and treatment of COVID-19
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DOI: 10.1007/s12598-021-01894-y
Abstract: The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed severe threats to human health, public safety, and the global economy. Metal nutrient elements can directly or indirectly take… read more here.
Keywords: metal; prevention treatment; treatment; pharmacology ... See more keywords
Third force in the treatment of COVID-19: A systematic review and meta-analysis
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DOI: 10.1016/j.amsu.2021.102218
Abstract: Background Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV2) depends on RNA-dependent RNA polymerase (RdRp) enzyme complex for its genomic replications and thus can be inhibited by nucleoside analogues. An example is Remdesivir, which is a non-obligate… read more here.
Keywords: treatment covid; review meta; analysis; treatment ... See more keywords
Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial
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DOI: 10.1016/j.ctim.2021.102769
Abstract: Background Effective treatment for Coronavirus Disease-2019 (COVID-19) is under intensive research. Nigella sativa oil (NSO) is a herbal medicine with antiviral and immunomodulatory activities, and has been recommended for the treatment of COVID-19. This study… read more here.
Keywords: medicine; treatment covid; trial; treatment ... See more keywords