IBRUTINIB VERSUS PLACEBO IN PATIENTS WITH ASYMPTOMATIC, TREATMENT‐NAÏVE EARLY STAGE CLL: PRIMARY ENDPOINT RESULTS OF THE PHASE 3 DOUBLE‐BLIND RANDOMIZED CLL12 TRIAL
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.7_2629
Abstract: RCHOP, HR 0.67 (95% CI 0.441.03), p (one-sided) =0.03 (Figure). The 2-year overall survival was 87% and 80%, respectively. Based on COO, PFS HR for R2CHOP was: 0.68 for ABC, p=0.15, 0.86 for GCB, 0.83… read more here.
Keywords: patients asymptomatic; placebo patients; versus placebo; asymptomatic treatment ... See more keywords
Treatment of early rheumatoid arthritis: Methotrexate and beyond.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2022.102227
Abstract: For the last several decades, the standard of care for the initial management of rheumatoid arthritis (RA) has been methotrexate. Methotrexate is effective as monotherapy and in combination with conventional, biologic, and targeted-synthetic therapies. Methotrexate… read more here.
Keywords: treatment early; rheumatoid arthritis; methotrexate; arthritis methotrexate ... See more keywords
Timing orthodontic treatment: early or late?
Sign Up to like & getrecommendations! Published in 2017 at "Australian Dental Journal"
DOI: 10.1111/adj.12474
Abstract: The timing of orthodontic interventions has been a contentious topic for many years with early treatment to address or indeed to prevent skeletal discrepancies in all three spatial planes and to alleviate crowding in common… read more here.
Keywords: intervention; treatment; early late; orthodontic treatment ... See more keywords
Screening for asymptomatic neurosyphilis in HIV patients after treatment of early syphilis: an observational study
Sign Up to like & getrecommendations! Published in 2017 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2016-052938
Abstract: Objective To determine the prevalence of asymptomatic neurosyphilis (ANS) in HIV-positive individuals after treatment of early syphilis with single-dose benzathine penicillin G (BPG) or oral antibiotic alternatives. Methods Patients at high risk of neurosyphilis (defined… read more here.
Keywords: early syphilis; syphilis; treatment; csf ... See more keywords
Clinical Application Study of Semi-cylindrical Beam Spoiler for Radiation Treatment of Early-stage Glottic Cancer Patients
Sign Up to like & getrecommendations! Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12795
Abstract: Background/Aim: The purpose of this study was to determine whether a semi-cylindrical beam spoiler (sCBS) developed herein effectively increases the skin dose in patients with early-stage glottic cancer. Patients and Methods: We measured the surface… read more here.
Keywords: treatment early; glottic cancer; stage glottic; early stage ... See more keywords
Ultrasound-guided microwave ablation in the treatment of early-stage tongue cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.950228
Abstract: Background Tongue cancer is a common malignant tumor of the head and neck. Its treatment methods include surgery, radiotherapy, and chemotherapy. However, these treatments have serious side effects and poor cosmetic effect, so it is… read more here.
Keywords: treatment early; tongue cancer; tongue; ultrasound guided ... See more keywords
[Consensus on fertility preservation treatment for early stage endometrial cancer and atypical hyperplasia].
Sign Up to like & getrecommendations! Published in 2019 at "Zhonghua fu chan ke za zhi"
DOI: 10.3760/cma.j.issn.0529-567x.2019.02.002
Abstract: 对于年轻子宫内膜非典型增生及早期子宫内膜样癌（G(1)，Ⅰa期）患者，在启动保留生育功能治疗前应进行包括病理、临床、影像学及宫腔镜在内的多学科全面评估，只有经严格选择的无保留生育功能治疗禁忌证的患者，在充分告知其手术切除子宫为首选治疗方案以及保留生育功能治疗的风险后方可启动保留生育功能治疗。大剂量高效孕激素为保留生育功能治疗的首选方案，宫腔镜全面评估和充分的病灶去除可能有助于提高保留生育功能治疗的疗效；治疗期间应定期评估疗效，完全缓解患者应根据有、无生育要求积极实施辅助生殖技术治疗或给予孕激素保护子宫内膜，并应长期严密随访以预防复发。. read more here.
Keywords: preservation treatment; consensus fertility; fertility preservation; stage endometrial ... See more keywords
Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Internal Medicine"
DOI: 10.7326/m22-3305
Abstract: Previous trials have shown the effects of fluvoxamine alone and inhaled budesonide alone for prevention of disease progression among outpatients with COVID-19. This placebo-controlled, randomized trial, conducted at 12 clinical sites in Brazil, sought to… read more here.
Keywords: inhaled budesonide; budesonide treatment; fluvoxamine inhaled; treatment early ... See more keywords