Zwitterionic Polymer Coating of Sulfur Dioxide-Releasing Nanosystem Augments Tumor Accumulation and Treatment Efficacy.
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DOI: 10.1002/adhm.201901582
Abstract: Multiple drug resistance (MDR) exhibited by cancer cells and low intratumor accumulation of chemotherapeutics are the main obstacles in cancer chemotherapy. Herein, the preparation of a redox-responsive sulfur dioxide (SO2 )-releasing nanosystem, with high SO2… read more here.
Keywords: accumulation; releasing nanosystem; tumor accumulation; sulfur dioxide ... See more keywords
Tracking the Progression of Osteolytic and Osteosclerotic Lesions in Mice Using Serial In Vivo μCT: Applications to the Assessment of Bisphosphonate Treatment Efficacy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3317
Abstract: The metastasis of tumor cells to bone can lead to osteolytic and osteosclerotic lesions, which cause severe, highly‐localized bone destruction and abnormal bone apposition, respectively. Accurate quantification of lesion progression is critical to understand underlying… read more here.
Keywords: osteolytic osteosclerotic; bone; osteosclerotic lesions; treatment efficacy ... See more keywords
Development and feasibility of the use of an assessment tool measuring treatment efficacy in patients with trimethylaminuria: A mixed methods study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12023
Abstract: Trimethylaminuria (TMAU) is a rare metabolic condition characterised by an unpleasant smell resembling rotting fish. Currently, the only measure of treatment efficacy is urine trimethylamine levels which do not always reflect the patient's experience of… read more here.
Keywords: assessment tool; treatment; tool; efficacy patients ... See more keywords
An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B-Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations.
Sign Up to like & getrecommendations! Published in 2025 at "Small methods"
DOI: 10.1002/smtd.202500945
Abstract: Acute Lymphoblastic Leukemia (ALL) accounts for over 25% of pediatric cancers. It affects lymphoid progenitor cells, leading to overproduction of immature B- or T-cells. ALL cells rely on asparagine for survival. Therefore, the addition of… read more here.
Keywords: treatment; treatment efficacy; acute lymphoblastic; lymphoblastic leukemia ... See more keywords
Reply to “Ultrasound evaluation of optic nerve sheath diameter to assess treatment efficacy in pediatric idiopathic intracranial hypertension”
Sign Up to like & getrecommendations! Published in 2020 at "Child's Nervous System"
DOI: 10.1007/s00381-020-04576-9
Abstract: Dear Editor: We would like to thank you for the opportunity to respond to the issues raised in Vitiello et al.’s letter. We also would like to thank Vitiello et al. [1] for their opinion… read more here.
Keywords: efficacy pediatric; sheath diameter; nerve sheath; optic nerve ... See more keywords
Immunosuppressive circuits in tumor microenvironment and their influence on cancer treatment efficacy
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DOI: 10.1007/s00428-018-2477-z
Abstract: It has been for long conceived that hallmarks of cancer were intrinsic genetic features driving tumor development, proliferation, and progression, and that targeting such cell-autonomous pathways could be sufficient to achieve therapeutic cancer control. Clinical ex… read more here.
Keywords: cancer; tumor microenvironment; treatment efficacy; tumor ... See more keywords
Prevalence of copy number variants (CNVs) and rhGH treatment efficacy in an Italian cohort of children born small for gestational age (SGA) with persistent short stature associated with a complex clinical phenotype
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DOI: 10.1007/s40618-021-01617-1
Abstract: Multiple factors influence intrauterine growth and lead to low birth sizes. The impact of genetic alterations on both pre- and post-natal growth is still largely unknown. The aim of this study was to investigate the… read more here.
Keywords: stature; stature associated; persistent short; short stature ... See more keywords
Performance of a microwave radiation induced persulfate-hydrogen peroxide binary-oxidant process in treating dinitrodiazophenol wastewater
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DOI: 10.1016/j.seppur.2019.116253
Abstract: Abstract A persulfate-hydrogen peroxide (PS-H2O2) binary-oxidant system activated by microwave (MW) radiation was used to treat dinitrodiazophenol (DDNP) industrial wastewater. While evaluating the treatment efficacy of the MW-PS-H2O2 process, the effects of MW power, PS… read more here.
Keywords: treatment; power; process; wastewater ... See more keywords
A single blood sample for stimulated LH assayed by ICMA is useful for monitoring the treatment efficacy of triptorelin depot in girls
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2148120
Abstract: Abstract Background: There is still no consensus on the optimal monitoring method to evaluate the hypothalamic-pituitary-gonadal axis (HPGA) inhibition. Methods: There were 124 girls treated with triptorelin depot due to puberty disorders, including 77 central… read more here.
Keywords: treatment efficacy; triptorelin depot; triptorelin; monitoring ... See more keywords
The challenge of establishing treatment efficacy for cutaneous vascular manifestations of systemic sclerosis
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DOI: 10.1080/1744666x.2018.1464390
Abstract: ABSTRACT Introduction: The cutaneous vascular manifestations of systemic sclerosis (SSc) comprise Raynaud’s phenomenon, cutaneous ulceration, telangiectasia formation and critical digital ischaemia; each of which are associated with significant disease-related morbidity. Despite the availability of multiple… read more here.
Keywords: cutaneous vascular; vascular manifestations; treatment efficacy; manifestations systemic ... See more keywords
A machine learning approach to predict treatment efficacy and adverse effects in major depression using CYP2C19 and clinical-environmental predictors
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DOI: 10.1097/ypg.0000000000000379
Abstract: Background Major depressive disorder (MDD) is among the leading causes of disability worldwide and treatment efficacy is variable across patients. Polymorphisms in cytochrome P450 2C19 (CYP2C19) play a role in response and side effects to… read more here.
Keywords: treatment; treatment efficacy; predict treatment; machine learning ... See more keywords