The heart of the matter: Right heart imaging indicators for treatment escalation in pulmonary arterial hypertension
Sign Up to like & getrecommendations! Published in 2023 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12240
Abstract: Abstract Right heart (RH) structure and function are major determinants of symptoms and prognosis in pulmonary arterial hypertension (PAH). RH imaging provides detailed information, but evidence and guidelines on the use of RH imaging in… read more here.
Keywords: survey; heart; pah; treatment escalation ... See more keywords
Transmural remission improves clinical outcomes up to 5 years in Crohn's disease
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12356
Abstract: Abstract Introduction Evidence supporting transmural remission (TR) as a long‐term treatment target in Crohn's disease (CD) is still unavailable. Less stringent but more reachable targets such as isolated endoscopic (IER) or radiologic remission (IRR) may… read more here.
Keywords: clinical outcomes; transmural remission; remission; crohn disease ... See more keywords
Trial designs and results supporting treatment de-escalation and escalation.
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DOI: 10.1016/j.breast.2017.06.020
Abstract: Trials for escalation and de-escalation of treatment aim to improve patient care, but from different sides of the same coin with respect to disease control and burdens of treatment. De-escalation of therapy is inherently a… read more here.
Keywords: trial designs; treatment escalation; treatment; designs results ... See more keywords
Mechanical Power Ratio and Respiratory Treatment Escalation in COVID-19 Pneumonia: A Secondary Analysis of a Prospectively Enrolled Cohort
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DOI: 10.1097/aln.0000000000004465
Abstract: Background: Under the hypothesis that mechanical power ratio could identify the spontaneously breathing patients with a higher risk of respiratory failure, this study assessed lung mechanics in nonintubated patients with COVID-19 pneumonia, aiming to (1)… read more here.
Keywords: treatment escalation; mechanical power; power ratio; power ... See more keywords
Adalimumab vs Infliximab in Pediatric Patients With Crohn's Disease: A Propensity Score Analysis and Predictors of Treatment Escalation
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Gastroenterology"
DOI: 10.14309/ctg.0000000000000490
Abstract: INTRODUCTION: Two antitumor necrosis factor therapies (infliximab [IFX] and adalimumab [ADA]) have been approved for the treatment of pediatric Crohn's disease (CD) but have not been compared in head-to-head trials. The aim of this study… read more here.
Keywords: propensity score; treatment escalation; treatment;