Treatment-free remission of chronic myeloid leukemia in real-world practice by the detection limit of MR4.3.
Sign Up to like & getrecommendations! Published in 2021 at "Leukemia research"
DOI: 10.1016/j.leukres.2021.106578
Abstract: BACKGROUND Molecular response (MR) 4.0 or 4.3 remains an indicator of treatment-free remission (TFR) in patients with chronic myeloid leukemia (CML) in countries that accept it as the criterion of undetectable minimal residual disease (UMRD)… read more here.
Keywords: treatment free; treatment; mr4; free remission ... See more keywords
Destructive-Treatment-Free Rapid Polymer-Assisted Metal Deposition for Versatile Electronic Textiles.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c19278
Abstract: Highly conductive, durable, and breathable metal-coated textiles are critical building block materials for future wearable electronics. In order to enhance the metal adhesion on the textile surface, existing solution-based approaches to preparing these materials require… read more here.
Keywords: treatment free; polymer assisted; assisted metal; rapid polymer ... See more keywords
Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission
Sign Up to like & getrecommendations! Published in 2019 at "Leukemia"
DOI: 10.1038/s41375-019-0647-x
Abstract: Approximately half of patients with chronic myeloid leukemia (CML) in sustained deep molecular response who discontinue tyrosine kinase inhibitors (TKIs) remain in treatment-free remission (TFR). Some of these patients have measurable residual disease (MRD) by… read more here.
Keywords: treatment free; myeloid leukemia; patients chronic; chronic myeloid ... See more keywords
Treatment-free remission in chronic myeloid leukemia: the patient perspective and areas of unmet needs
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0867-0
Abstract: In CML, treatment-free remission (TFR) refers to having a stable deep molecular response without the need for ongoing tyrosine kinase inhibitor treatment. Whilst recommendations exist about the technical management of stopping and re-starting therapy, much… read more here.
Keywords: treatment free; areas unmet; treatment; patient perspective ... See more keywords
A sample pre-treatment-free electrochemical immunosensor with negative electro-pulsion for the quantitative detection of acrylamide in coffee, cocoa and prune juice
Sign Up to like & getrecommendations! Published in 2019 at "Analytical Methods"
DOI: 10.1039/c9ay01102a
Abstract: Displacement of an antibody enhanced by negative electro-pulsion. read more here.
Keywords: electro pulsion; sample pre; pre treatment; negative electro ... See more keywords
Emerging concepts for assessing and predicting treatment-free remission in chronic myeloid leukemia patients
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2022.2018296
Abstract: ABSTRACT Introduction In chronic myeloid leukemia (CML) patients who have reached a deep and sustained reduction of residual disease can attempt a discontinuation. The ‘treatment-free remission’ (TFR) has become a real long-term endpoint for 30–40%… read more here.
Keywords: myeloid leukemia; free remission; treatment free; chronic myeloid ... See more keywords
Abstract 2181: Treatment-free remission after discontinuation of ALK tyrosine kinase inhibitors (TKIs) in patients with ALK-positive anaplastic large cell lymphoma (ALCL)
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2181
Abstract: Introduction: ALK-positive ALCL accounts for 0.8% of Korean lymphoma patients. ALK TKIs are effective and durable, but clinical outcomes after treatment discontinuation are unknown. We analyzed outcomes and minimal residual disease (MRD) in adult ALK-positive… read more here.
Keywords: treatment free; free remission; alk positive; alk ... See more keywords
Treatment-Free Remission in Real-World Chronic Myeloid Leukemia Patients: Insights from German Hematology Practices
Sign Up to like & getrecommendations! Published in 2022 at "Acta Haematologica"
DOI: 10.1159/000525935
Abstract: Introduction: Treatment-free remission (TFR) is increasingly considered as treatment goal for patients with chronic myeloid leukemia (CML), but information on the disposition and outcome of TFR in clinical practice is scarce. Here, we report the… read more here.
Keywords: treatment free; free remission; hematology; treatment ... See more keywords
Late molecular recurrences in patients with chronic myeloid leukemia experiencing treatment-free remission.
Sign Up to like & getrecommendations! Published in 2020 at "Blood advances"
DOI: 10.1182/bloodadvances.2020001772
Abstract: Treatment-free remission (TFR) is an opportunity for patients with chronic myeloid leukemia (CML). Reported cumulative incidence curves of molecular recurrence (MRec) arbor a 2-phase shape with mainly early events, but also some late events (late… read more here.
Keywords: treatment free; myeloid leukemia; free remission; patients chronic ... See more keywords
Association of TIM-3 checkpoint receptor expression on T cells with treatment-free remission in chronic myeloid leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008854
Abstract: Key Points • TIM-3 is the only immune-checkpoint receptor consistently overexpressed in patients with CML who relapse after TKI cessation.• Overexpression of TIM-3 provides a rationale to test TIM-3 inhibitors to modify treatment-free remission outcomes. read more here.
Keywords: tim; checkpoint receptor; treatment free; free remission ... See more keywords
Treatment-free survival (TFS), a novel outcome applied to immuno-oncology (IO) agents in advanced melanoma (AM).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.9531
Abstract: 9531Background: Conventional measures, such as median progression-free survival, may suboptimally characterize the full impact of IO agents. Patients (pts) discontinuing IO agents may experience pe... read more here.
Keywords: survival tfs; treatment free; free survival; tfs novel ... See more keywords