Articles with "treatment glycosphingolipid" as a keyword



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Treatment with the Glycosphingolipid Modulator THI Rescues Myelin Integrity in the Striatum of R6/2 HD Mice

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24065956

Abstract: Huntington’s disease is one of the most common dominantly inherited neurodegenerative disorders caused by an expansion of a polyglutamine (polyQ) stretch in the N-terminal region of huntingtin (Htt). Among all the molecular mechanisms, affected by… read more here.

Keywords: striatum mice; modulator thi; glycosphingolipid modulator; treatment glycosphingolipid ... See more keywords