Optimal Pharmacologic Treatment of Heart Failure With Preserved and Mildly Reduced Ejection Fraction
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.31963
Abstract: Key Points Question What is the optimal drug combination for treatment of heart failure (HF) with preserved ejection fraction (HFpEF) and mildly reduced ejection fraction (HFmrEF)? Findings In this network meta-analysis, 19 randomized clinical trials… read more here.
Keywords: treatment heart; heart failure; failure preserved; ejection ... See more keywords
Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A1 Receptor Agonist for the Chronic Treatment of Heart Diseases
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DOI: 10.1002/cmdc.201700151
Abstract: Adenosine is known to be released under a variety of physiological and pathophysiological conditions to facilitate the protection and regeneration of injured ischemic tissues. The activation of myocardial adenosine A1 receptors (A1Rs) has been shown to… read more here.
Keywords: a1r; agonist; treatment heart; bialanate hydrochloride ... See more keywords
A Review of the Proposed Mechanistic Actions of Sodium Glucose Cotransporter-2 Inhibitors in the Treatment of Heart Failure
Sign Up to like & getrecommendations! Published in 2021 at "Cardiology Research"
DOI: 10.14740/cr1221
Abstract: Diabetes mellitus is a well-known risk factor for heart failure, and the reasons why are well understood. The incidence of diabetes mellitus is continuing to rise, posing a major concern in the medical world. The… read more here.
Keywords: heart; sodium glucose; treatment heart; heart failure ... See more keywords
Biological and In silico Studies on Synthetic Analogues of Tyrosine Betaine as Inhibitors of Neprilysin - A Drug Target for the Treatment of Heart Failure.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666180515114236
Abstract: BACKGROUND Fungal secondary metabolites are important sources for the discovery of new pharmaceuticals, as exemplified by penicillin, lovastatin and cyclosporine. Searching for secondary metabolites of the fungi Metarhizium spp., we previously identified tyrosine betaine as… read more here.
Keywords: heart failure; treatment heart; tyrosine betaine; inhibitors neprilysin ... See more keywords
The chemical components, action mechanisms, and clinical evidences of YiQiFuMai injection in the treatment of heart failure
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1040235
Abstract: YiQiFuMai injection (YQFM), derived from Shengmai Powder, is wildly applied in the treatment of cardiovascular diseases, such as coronary heart disease and chronic cardiac insufficiency. YiQiFuMai injection is mainly composed of Radix of Panax ginseng… read more here.
Keywords: injection; yiqifumai injection; treatment heart; injection treatment ... See more keywords
The Current Therapeutic Role of Chromatin Remodeling for the Prognosis and Treatment of Heart Failure
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020579
Abstract: Cardiovascular diseases are a major cause of death globally, with no cure to date. Many interventions have been studied and suggested, of which epigenetics and chromatin remodeling have been the most promising. Over the last… read more here.
Keywords: treatment heart; chromatin remodeling; heart failure; heart ... See more keywords