Glutamine synthetase-negative hepatocellular carcinoma has better prognosis and response to sorafenib treatment after hepatectomy.
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DOI: 10.1097/cm9.0000000000002380
Abstract: BACKGROUND Glutamine synthetase (GS) and arginase 1 (Arg1) are widely used pathological markers that discriminate hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma; however, their clinical significance in HCC remains unclear. METHODS We retrospectively analyzed 431 HCC… read more here.
Keywords: treatment hepatectomy; prognosis; hcc; sorafenib treatment ... See more keywords