An O-Benzyl Phosphonamidate Prodrug of Tenofovir for the Treatment of Hepatitis B Virus Infection.
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DOI: 10.1021/acs.jmedchem.2c00869
Abstract: A series of new O-(substituted benzyl) phosphoramidate prodrugs of tenofovir for the treatment of hepatitis B virus (HBV) infections have been designed and synthesized. An investigation of structure-activity relationships revealed that the compound bearing an… read more here.
Keywords: tenofovir; benzyl; hepatitis virus; treatment hepatitis ... See more keywords
Treatment of hepatitis C with new fixed dose combinations
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DOI: 10.1080/14656566.2017.1346609
Abstract: ABSTRACT Introduction: The advent of oral direct-acting antivirals (DAA) has revolutionized the hepatitis C virus (HCV) therapeutic landscape providing cure rates over 90%. However, a subset of patients remains at higher risk for treatment failure,… read more here.
Keywords: treatment; dose combinations; treatment hepatitis; fixed dose ... See more keywords
Sofosbuvir + velpatasvir + voxilaprevir for the treatment of hepatitis C infection
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DOI: 10.1080/14656566.2018.1459567
Abstract: ABSTRACT Introduction: Hepatitis C is a disease with a significant global impact. Over the last several years, the treatment of the disease has been revolutionized. Therapy has transformed over the last several years with the… read more here.
Keywords: sofosbuvir velpatasvir; hepatitis; treatment; treatment hepatitis ... See more keywords
Sofosbuvir plus ribavirin for the treatment of hepatitis C virus genotype 2 in Korea: What's the optimal dosage of ribavirin in real‐world setting?
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DOI: 10.1111/1751-2980.12695
Abstract: This study aimed to investigate the efficacy and safety of sofosbuvir plus ribavirin for the treatment of hepatitis C virus (HCV) genotype 2 infection and to determine the optimal ribavirin dosage. read more here.
Keywords: sofosbuvir plus; hepatitis virus; treatment hepatitis; plus ribavirin ... See more keywords
Experiences of Hope after Treatment of Hepatitis C Infection—A Qualitative Study
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DOI: 10.3390/ijerph192315732
Abstract: The aim of this study was to explore the experiences of hope people had after undergoing treatment for a hepatitis C virus infection (HCV). Between October 2019 and May 2020, 19 one-on-one interviews were conducted… read more here.
Keywords: experiences hope; turning gaze; treatment hepatitis; treatment ... See more keywords
Hepatitis C virus: A critical approach to who really needs treatment
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DOI: 10.4254/wjh.v14.i1.1
Abstract: Introduction of effective drugs in the treatment of hepatitis C virus (HCV) infection has prompted the World Health Organization to declare a global eradication target by 2030. Propositions have been made to screen the general… read more here.
Keywords: hcv; treatment; hepatitis virus; treatment hepatitis ... See more keywords