Treatment of HIV Infections with HIV Integrase Inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.6b00456
Abstract: Human immunodeficiency virus (HIV) infections and related diseases remain as major public health problems worldwide. The replication of HIV type 1 (HIV-1) requires the actions of three essential enzymes: reverse transcriptase, protease, and integrase. There… read more here.
Keywords: integrase inhibitors; infections hiv; hiv infections; hiv ... See more keywords
An up-to-date evaluation of dolutegravir/abacavir/lamivudine for the treatment of HIV
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2029409
Abstract: ABSTRACT Introduction There are more than 30 agents available for the treatment of HIV with guidelines shifting toward integrase strand transfer inhibitors (INSTIs) as part of first line therapy. The fixed dose combination of dolutegravir… read more here.
Keywords: treatment hiv; hiv; treatment; dolutegravir ... See more keywords
A safety evaluation of raltegravir for the treatment of HIV
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2018.1411903
Abstract: ABSTRACT Introduction: Raltegravir (RAL) was the first commercialized agent from a new drug class with an innovative target, the integrase. Since its introduction in clinical practice RAL has become widely used for the treatment of… read more here.
Keywords: treatment; treatment hiv; safety; safety evaluation ... See more keywords
Antiretroviral treatment for HIV infection: Swedish recommendations 2016
Sign Up to like & getrecommendations! Published in 2017 at "Infectious Diseases"
DOI: 10.1080/23744235.2016.1247495
Abstract: Abstract The Swedish Medical Products Agency and the Swedish Reference Group for Antiviral Therapy (RAV) have jointly published recommendations for the treatment of HIV infection on seven previous occasions (2002, 2003, 2005, 2007, 2009, 2011… read more here.
Keywords: medicine; hiv infection; treatment hiv; case ... See more keywords
How about the quality and recommendation on prevention, diagnosis, and treatment of HIV/AIDS guidelines developed by WHO
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000023638
Abstract: Abstract Background: Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) has become a pandemic that has infected millions of people around the world and brings a tremendous economic burden. There are numerous guidelines for prevention, diagnosis,… read more here.
Keywords: diagnosis treatment; quality; hiv aids; prevention diagnosis ... See more keywords
Dolutegravir-Rilpivirine, Dual Antiretroviral Therapy for the Treatment of HIV-1 Infection
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Pharmacotherapy"
DOI: 10.1177/1060028019831674
Abstract: Objective: To review the efficacy and safety of dolutegravir (DTG) with rilpivirine (RPV) as a dual therapy regimen in the treatment of HIV-1 infection. Data Sources: A literature search was performed using PubMed (1966 to… read more here.
Keywords: therapy; hiv infection; treatment hiv; dual therapy ... See more keywords
Ibalizumab: The First Monoclonal Antibody for the Treatment of HIV-1 Infection
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Pharmacotherapy"
DOI: 10.1177/1060028020942218
Abstract: Objective: To review the efficacy and safety of ibalizumab (IBA) in the treatment of HIV-1 infection. Data Sources: A literature search was performed using PubMed and Google Scholar (2010 to mid-June 2020) with the search… read more here.
Keywords: hiv infection; treatment; treatment hiv; ibalizumab ... See more keywords
Efficacy and safety of abacavir/lamivudine plus rilpivirine as a first-line regimen in treatment-naïve HIV-1 infected adults
Sign Up to like & getrecommendations! Published in 2020 at "AIDS Research and Therapy"
DOI: 10.1186/s12981-020-00272-5
Abstract: Background The anti-retroviral combination of abacavir/lamivudine plus rilpivirine (ABC/3TC/RPV) is not recommended by international guidelines as the first-line regimen. However, it is potent, well-tolerated, and affordable, especially in resource-limited settings. This study evaluates the efficacy and… read more here.
Keywords: treatment; treatment hiv; group; abacavir lamivudine ... See more keywords
Bone deleterious effects of different nrtis in treatment-naïve HIV patients after 12 and 48 weeks of treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Current HIV research"
DOI: 10.2174/1570162x19666210805094434
Abstract: BACKGROUND Bone alterations have been observed in the course of HIV infection, characterized by a marked decrease in bone mineral density (BMD) and an increase in the frequency of fractures as a result of fragility.… read more here.
Keywords: treatment; hiv patients; treatment hiv; bone ... See more keywords
Predicting Post-treatment HIV Remission: Does Size of the Viral Reservoir Matter?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.648434
Abstract: Combination antiretroviral therapy (ART) suppresses human immunodeficiency virus (HIV) replication and improves immune function. However, due to the persistence of long-lived HIV reservoirs, therapy interruption almost inevitably leads to a fast viral rebound. A small… read more here.
Keywords: reservoir; hiv; treatment hiv; post treatment ... See more keywords
Hybrid Molecules as Potential Drugs for the Treatment of HIV: Design and Applications
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091092
Abstract: Human immunodeficiency virus (HIV) infection is a major problem for humanity because HIV is constantly changing and developing resistance to current drugs. This necessitates the development of new anti-HIV drugs that take new approaches to… read more here.
Keywords: hybrid molecules; hiv; molecules potential; treatment hiv ... See more keywords