Characterization of novel compounds that directly bind to and inactivate the HPV E6 protein for treatment of HPV-associated cervical and oropharyngeal cancers.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.e15122
Abstract: e15122 Background: The human papillomavirus (HPV) E6 protein is necessary for viral genome replication and is always expressed in HPV-induced malignancies. We performed in silico screening of chemical libraries for molecules that bind to a… read more here.
Keywords: hpv; hpv protein; tumor; cell ... See more keywords
Prevention and Treatment of HPV-Induced Skin Tumors
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15061709
Abstract: Simple Summary Non-melanoma skin cancer is the most common cancer in humans and has been linked to skin infections with betaHPV. This has led to the development of vaccine candidates against these viruses. This review… read more here.
Keywords: prevention treatment; induced skin; hpv induced; skin tumors ... See more keywords