An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity.
Sign Up to like & getrecommendations! Published in 2020 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2019.12.025
Abstract: PURPOSE To examine the combined effects of common genetic variants associated with intraocular pressure (IOP) on primary open-angle glaucoma (POAG) phenotype using a polygenic risk score (PRS) stratification. DESIGN Cross-sectional study. PARTICIPANTS For the primary… read more here.
Keywords: risk group; risk; treatment intensity; family members ... See more keywords
Physician and patient perceptions on randomization of treatment intensity for unfit adults with acute myeloid leukemia and other high-grade myeloid neoplasm
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DOI: 10.1038/s41375-022-01524-1
Abstract: TO THE EDITOR Acute myeloid leukemia (AML) primarily affects older people, and thus many patients are felt to be medically less-than-fit (“unfit”) at the time of initial diagnosis (e.g., because of comorbid illnesses). How best… read more here.
Keywords: myeloid neoplasm; treatment; leukemia; treatment intensity ... See more keywords
Treatment intensity and survival in patients with relapsed or refractory diffuse large B-cell lymphoma in Denmark: a real-life population-based study
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DOI: 10.2147/clep.s178003
Abstract: Purpose High-dose chemotherapy with autologous stem cell transplantation (ASCT) is considered to be the only curative treatment option for patients with refractory or relapsed diffuse large B-cell lymphoma (DLBCL). Due to toxicity, not all patients… read more here.
Keywords: survival patients; salvage; treatment; salvage regimens ... See more keywords
Effects of lipid-lowering treatment intensity and adherence on cardiovascular outcomes in patients with a recent myocardial infarction: a Swedish register-based study
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DOI: 10.48101/ujms.v127.8296
Abstract: Background Oral lipid-lowering treatment (LLT) is the standard of care for patients with cardiovascular disease (CVD). However, insufficient treatment intensity and poor adherence can lead to suboptimal treatment benefit, rendering patients at increased risk of… read more here.
Keywords: intensity adherence; treatment intensity; adherence; llt intensity ... See more keywords