Clinical considerations in the early treatment of invasive mould infections and disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx031
Abstract: Different therapeutic strategies for invasive fungal diseases have been explored, each with particular strengths and weaknesses. Broad-spectrum antifungal prophylaxis seems logical, but selective use is important due to its substantial disadvantages, including interference with diagnostic… read more here.
Keywords: high risk; pre emptive; treatment; invasive fungal ... See more keywords
Diagnosis and treatment of invasive fungal infections: looking ahead
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkz041
Abstract: Improved standards of care depend on the development of new laboratory diagnostic and imaging procedures and the development of new antifungal compounds. Immunochromatography technologies have led to the development of lateral flow devices for the… read more here.
Keywords: diagnosis; diagnosis treatment; infections looking; fungal infections ... See more keywords
#78: Use of Isavuconazonium for Treatment Of Invasive Fungal Infection in Immunocompromised Pediatric Patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piaa170.006
Abstract: Isavuconazole (ISZ), dosed as the pre-drug isavuconazonium (ISM), is active against a wide variety of clinically important fungal pathogens. ISM is approved for the treatment of invasive aspergillosis and mucormycosis in adults ≥18 years of… read more here.
Keywords: pediatric patients; ism; fungal infection; treatment invasive ... See more keywords
Isavuconazole for the Treatment of Invasive Mold Disease in Solid Organ Transplant Recipients: A Multicenter Study on Efficacy and Safety in Real-life Clinical Practice
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation"
DOI: 10.1097/tp.0000000000004312
Abstract: Background. Isavuconazole has theoretical advantages over other mold-active triazoles for the treatment of invasive aspergillosis and mucormycosis after solid organ transplantation (SOT). The available clinical experience, nevertheless, is scarce. Methods. We performed a retrospective study… read more here.
Keywords: invasive mold; mold disease; therapy; treatment invasive ... See more keywords
Advances in the treatment of invasive fungal disease
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011322
Abstract: With over 300 million severe cases and 1.5 million deaths annually, invasive fungal diseases (IFDs) are a major medical burden and source of global morbidity and mortality. The World Health Organization (WHO) recently released the… read more here.
Keywords: fungal disease; advances treatment; health; invasive fungal ... See more keywords
Clinical research advances of isavuconazole in the treatment of invasive fungal diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1049959
Abstract: Purpose Invasive fungal diseases (IFD) are a major global public health concern. The incidence of IFD has increased the demand for antifungal agents. Isavuconazole (ISA) is a new triazole antifungal agent that has shown promising… read more here.
Keywords: invasive fungal; treatment invasive; efficacy; fungal diseases ... See more keywords
Diagnosis and Treatment of Invasive Candidiasis
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11060718
Abstract: Candida species, belonging to commensal microbial communities in humans, cause opportunistic infections in individuals with impaired immunity. Pathogens encountered in more than 90% cases of invasive candidiasis include C. albicans, C. glabrata, C. krusei, C.… read more here.
Keywords: diagnosis treatment; candidiasis; treatment invasive; invasive candidiasis ... See more keywords
Treatment of Invasive Candidiasis: A Narrative Review
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Fungi"
DOI: 10.3390/jof4030097
Abstract: Invasive candidiasis occurs frequently in hospitalized patients, and is associated with high mortality rates due to delays in recognition and initiation of appropriate antifungals. Management of invasive candidiasis must take into account multiple host, pathogen,… read more here.
Keywords: invasive candidiasis; candidiasis; candidiasis narrative; narrative review ... See more keywords
GR-2397: Review of the Novel Siderophore-like Antifungal Agent for the Treatment of Invasive Aspergillosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8090909
Abstract: GR-2397 (previously VL-2397, ASP2397) is a first-in-class antifungal agent for the treatment of invasive aspergillosis. This siderophore-like molecule resembles ferrichrome; however, it is differentiated by three amino acid changes and an aluminum rather than iron… read more here.
Keywords: agent treatment; antifungal agent; treatment invasive; treatment ... See more keywords
Isavuconazole Treatment for Invasive Fungal Infections in Pediatric Patients
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15030375
Abstract: This work’s objective was to evaluate the safety of isavuconazole (ISA) as a treatment or prophylaxis for invasive fungal infections (IFIs) in immunocompromised children. IFI was reported as proven or probable according to international definitions.… read more here.
Keywords: fungal infections; infections pediatric; isavuconazole treatment; treatment invasive ... See more keywords