Novel combination approaches with targeted agents in frontline chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34510
Abstract: Targeted therapies have revolutionized the frontline treatment landscape for patients with chronic lymphocytic leukemia (CLL) and have largely displaced a reliance on chemoimmunotherapy when treating this disease. Multiple randomized trials have documented the efficacy of… read more here.
Keywords: chronic lymphocytic; treatment landscape; combination; lymphocytic leukemia ... See more keywords
The Treatment Landscape and New Opportunities of Molecular Targeted Therapies in Gastroenteropancreatic Neuroendocrine Tumors
Sign Up to like & getrecommendations! Published in 2017 at "Targeted Oncology"
DOI: 10.1007/s11523-017-0532-3
Abstract: Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms that originate from neuroendocrine stem cells and express both neural and endocrine markers. They are found in almost every organ, and while NENs are mostly associated… read more here.
Keywords: treatment landscape; landscape new; treatment; molecular targeted ... See more keywords
Treatment landscape of metastatic pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2021.102180
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of cancer with a dismal prognosis. The lack of symptoms in the early phase of the disease makes early diagnosis challenging, and about 80-85% of the patients… read more here.
Keywords: metastatic pancreatic; treatment landscape; line; treatment ... See more keywords
The treatment landscape of advanced angiosarcoma in Asia—A multi‐national collaboration from the Asian Sarcoma Consortium
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Science"
DOI: 10.1111/cas.14793
Abstract: Angiosarcoma (AS) is a rare disease with a dismal prognosis. The treatment landscape and prognostic factors for advanced AS, including locally advanced, unresectable, and metastatic disease remain elusive. The Asian Sarcoma Consortium is an international… read more here.
Keywords: asian sarcoma; treatment; sarcoma consortium; treatment landscape ... See more keywords
Prophylaxis in children with haemophilia in an evolving treatment landscape
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DOI: 10.1111/hae.14412
Abstract: For children with haemophilia, early initiation of prophylaxis is crucial to prevent life‐threatening bleeds and maintain joint health throughout life. Options for prophylaxis have recently increased from replacement therapy with standard or extended half‐life coagulation… read more here.
Keywords: children haemophilia; treatment landscape; prophylaxis; haemophilia evolving ... See more keywords
Evolving treatment landscape of immunotherapy in breast cancer: current issues and future perspectives
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221146129
Abstract: Immune checkpoint inhibitors (ICIs) deeply changed the treatment landscape of breast cancer (BC). In particular, anti-programmed-death (ligand) 1 antibodies were approved for the treatment of triple-negative breast cancer (TNBC), both in first line for metastatic… read more here.
Keywords: breast cancer; treatment; treatment landscape;
Circulating tumour DNA in the evolving treatment landscape of locally advanced rectal cancer: where does it fit in?
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359231160138
Abstract: The management of locally advanced rectal cancer (LARC) requires multimodality treatment, typically with neoadjuvant chemoradiotherapy (CRT) followed by total mesorectal excision. However, the treatment landscape is rapidly evolving with total neoadjuvant therapy and non-operative management… read more here.
Keywords: locally advanced; ctdna; treatment landscape; treatment ... See more keywords
Impact of new chemotherapy regimens on the treatment landscape and survival of advanced pancreatic cancer (PAC) patients (pts).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.403
Abstract: 403 Background: The clinical phase III first-line trials MPACT and PRODIGE4/ACCORD11 in metastatic PAC pts have changed the treatment paradigm. We aimed to analyse the impact of these regimens on the treatment landscape and survival… read more here.
Keywords: treatment landscape; treatment; regimens treatment; line ... See more keywords
The rapidly evolving treatment landscape for patients with brain metastases from epidermal growth factor receptor mutated non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Translational lung cancer research"
DOI: 10.21037/tlcr.2017.10.14
Abstract: While this quote is likely apocryphal and not, as is commonly attributed, a curse of Chinese origin (1), its ironic sentiment seems apt when one considers the rapidly shifting treatment landscape for patients with brain… read more here.
Keywords: brain metastases; treatment landscape; patients brain; lung cancer ... See more keywords
Current Treatment Landscape for Advanced Hepatocellular Carcinoma: Patient Outcomes and the Impact on Quality of Life
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11060841
Abstract: Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer mortality worldwide. Heterogeneity of clinical conditions contributes to the complex management of care for patients with advanced HCC. Recently,… read more here.
Keywords: hepatocellular carcinoma; treatment landscape; treatment; landscape advanced ... See more keywords
Immune Checkpoint Inhibitors: Changing the Treatment Landscape in Esophagogastric Adenocarcinoma
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DOI: 10.3390/ph16010102
Abstract: In the West, recent decades have demonstrated an epidemiological trend towards esophago-gastric adenocarcinomas (EGAC), with considerable associated mortality. Historically, chemotherapy has represented the sole systemic treatment option in the advanced EGAC setting, in addition to… read more here.
Keywords: changing treatment; checkpoint inhibitors; immune checkpoint; treatment landscape ... See more keywords