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Published in 2020 at "Molecular biology reports"
DOI: 10.1007/s11033-020-05886-6
Abstract: Despite the depth of knowledge concerning the pathogenesis of melanoma, the most aggressive type of skin cancer, the prognosis and survival of patients still remain a challenge. In addition, responses to chemotherapy and immunotherapy are…
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Keywords:
melanoma;
treatment melanoma;
role autophagy;
pathogenesis ... See more keywords
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Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00775
Abstract: Melanoma is one of the most severe cancerous diseases. The cells employ multiple signaling pathways, such as ERK, HGF/c-MET, WNT, and COX-2 to cause the cell proliferation, survival, and metastasis. Treatment of melanoma, including surgery,…
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Keywords:
novel delivery;
melanoma;
treatment melanoma;
delivery systems ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16878-1
Abstract: Dacarbazine (DZ) is poorly soluble in water with the short half-life in blood circulation, low rate of response with the toxic effect which ultimately limits its utilization of the treatment of skin cancer. In view…
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Keywords:
treatment melanoma;
dacarbazine;
dacarbazine nanoparticle;
nanoparticle ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46287-5
Abstract: Melanoma is the most serious form of skin cancer but its medication is still far from being safe and thoroughly effective. The search of novel therapeutic approaches represents therefore a health emergency to push through…
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Keywords:
melanoma;
dual kit;
treatment melanoma;
kit aur ... See more keywords
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Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr05323e
Abstract: The development of therapeutic methods that can effectively delay tumor growth, inhibit tumor metastases, and protect the host from tumor recurrence still faces challenges. Nanoparticle-based combination therapy may provide an effective therapeutic strategy. Herein, we…
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Keywords:
melanoma;
loaded immunoadjuvant;
immunotherapy;
bsa ... See more keywords
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Published in 2019 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2019.1694664
Abstract: ABSTRACT Introduction: In the treatment of advanced BRAF-mutant melanoma, selective regulation of the MAPK pathway with BRAF and MEK inhibition has emerged as one of the mainstays of therapy. Areas covered: The authors present the…
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Keywords:
melanoma;
evaluation encorafenib;
treatment melanoma;
treatment ... See more keywords
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Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1762561
Abstract: ABSTRACT Introduction Immune therapies have dramatically changed the treatment landscape for melanoma in the past decade. Ipilimumab, nivolumab, and pembrolizumab have been approved by U.S. Food and Drug Administration for the treatment of metastatic melanoma…
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Keywords:
melanoma;
treatment melanoma;
treatment;
toripalimab treatment ... See more keywords
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Published in 2023 at "Drugs of today"
DOI: 10.1358/dot.2023.59.2.3509756
Abstract: Melanoma is a highly lethal type of skin cancer. Although an early diagnosis, in combination with surgery for nonmetastatic melanomas, significantly increases the probability of survival, there are no efficacious treatments for metastatic melanoma. Nivolumab…
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Keywords:
nivolumab relatlimab;
melanoma nivolumab;
treatment melanoma;
melanoma ... See more keywords
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Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.728113
Abstract: 1 University of Sassari & Unit of Cancer Genetics, National Research Council (CNR), Sassari, Italy, 2 Roswell Park Comprehensive Cancer Center, University of Buffalo, Buffalo, NY, United States, 3 Section of Pathology, Department of Health…
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Keywords:
melanoma;
advancements molecular;
diagnosis treatment;
treatment melanoma ... See more keywords
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Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20092207
Abstract: Antigen peptides and adjuvants have been extensively investigated for cancer immunotherapy, and they are expected to elicit specific immune responses for cancer treatment. However, the anti-cancer efficacy of antigen peptide and adjuvant-based cancer vaccines has…
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Keywords:
treatment melanoma;
treatment;
cpg lipovaccines;
sl9 cpg ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102090
Abstract: Melanoma can be divided into cutaneous melanoma, uveal melanoma, mucosal melanoma, etc. It is a very aggressive tumor that is prone to metastasis. Patients with metastatic melanoma have a poor prognosis and shorter survival. Although…
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Keywords:
advances application;
melanoma;
nanomaterials treatment;
treatment melanoma ... See more keywords