New insights on the role of autophagy in the pathogenesis and treatment of melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular biology reports"
DOI: 10.1007/s11033-020-05886-6
Abstract: Despite the depth of knowledge concerning the pathogenesis of melanoma, the most aggressive type of skin cancer, the prognosis and survival of patients still remain a challenge. In addition, responses to chemotherapy and immunotherapy are… read more here.
Keywords: melanoma; treatment melanoma; role autophagy; pathogenesis ... See more keywords
Options of Therapeutics and Novel Delivery Systems of Drugs for the Treatment of Melanoma.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00775
Abstract: Melanoma is one of the most severe cancerous diseases. The cells employ multiple signaling pathways, such as ERK, HGF/c-MET, WNT, and COX-2 to cause the cell proliferation, survival, and metastasis. Treatment of melanoma, including surgery,… read more here.
Keywords: novel delivery; melanoma; treatment melanoma; delivery systems ... See more keywords
Dacarbazine nanoparticle topical delivery system for the treatment of melanoma
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16878-1
Abstract: Dacarbazine (DZ) is poorly soluble in water with the short half-life in blood circulation, low rate of response with the toxic effect which ultimately limits its utilization of the treatment of skin cancer. In view… read more here.
Keywords: treatment melanoma; dacarbazine; dacarbazine nanoparticle; nanoparticle ... See more keywords
Dual Kit/Aur Inhibitors as Chemosensitizing Agents for the Treatment of Melanoma: Design, Synthesis, Docking Studies and Functional Investigation
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46287-5
Abstract: Melanoma is the most serious form of skin cancer but its medication is still far from being safe and thoroughly effective. The search of novel therapeutic approaches represents therefore a health emergency to push through… read more here.
Keywords: melanoma; dual kit; treatment melanoma; kit aur ... See more keywords
BSA-bioinspired gold nanorods loaded with immunoadjuvant for the treatment of melanoma by combined photothermal therapy and immunotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr05323e
Abstract: The development of therapeutic methods that can effectively delay tumor growth, inhibit tumor metastases, and protect the host from tumor recurrence still faces challenges. Nanoparticle-based combination therapy may provide an effective therapeutic strategy. Herein, we… read more here.
Keywords: melanoma; loaded immunoadjuvant; immunotherapy; bsa ... See more keywords
An evaluation of encorafenib for the treatment of melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2019.1694664
Abstract: ABSTRACT Introduction: In the treatment of advanced BRAF-mutant melanoma, selective regulation of the MAPK pathway with BRAF and MEK inhibition has emerged as one of the mainstays of therapy. Areas covered: The authors present the… read more here.
Keywords: melanoma; evaluation encorafenib; treatment melanoma; treatment ... See more keywords
Toripalimab for the treatment of melanoma
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1762561
Abstract: ABSTRACT Introduction Immune therapies have dramatically changed the treatment landscape for melanoma in the past decade. Ipilimumab, nivolumab, and pembrolizumab have been approved by U.S. Food and Drug Administration for the treatment of metastatic melanoma… read more here.
Keywords: melanoma; treatment melanoma; treatment; toripalimab treatment ... See more keywords
Nivolumab and relatlimab for the treatment of melanoma.
Sign Up to like & getrecommendations! Published in 2023 at "Drugs of today"
DOI: 10.1358/dot.2023.59.2.3509756
Abstract: Melanoma is a highly lethal type of skin cancer. Although an early diagnosis, in combination with surgery for nonmetastatic melanomas, significantly increases the probability of survival, there are no efficacious treatments for metastatic melanoma. Nivolumab… read more here.
Keywords: nivolumab relatlimab; melanoma nivolumab; treatment melanoma; melanoma ... See more keywords
Editorial: Advancements in Molecular Diagnosis and Treatment of Melanoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.728113
Abstract: 1 University of Sassari & Unit of Cancer Genetics, National Research Council (CNR), Sassari, Italy, 2 Roswell Park Comprehensive Cancer Center, University of Buffalo, Buffalo, NY, United States, 3 Section of Pathology, Department of Health… read more here.
Keywords: melanoma; advancements molecular; diagnosis treatment; treatment melanoma ... See more keywords
Nanostructured SL9-CpG Lipovaccines Elicit Immune Response for the Treatment of Melanoma
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20092207
Abstract: Antigen peptides and adjuvants have been extensively investigated for cancer immunotherapy, and they are expected to elicit specific immune responses for cancer treatment. However, the anti-cancer efficacy of antigen peptide and adjuvant-based cancer vaccines has… read more here.
Keywords: treatment melanoma; treatment; cpg lipovaccines; sl9 cpg ... See more keywords
Advances in the Application of Nanomaterials to the Treatment of Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102090
Abstract: Melanoma can be divided into cutaneous melanoma, uveal melanoma, mucosal melanoma, etc. It is a very aggressive tumor that is prone to metastasis. Patients with metastatic melanoma have a poor prognosis and shorter survival. Although… read more here.
Keywords: advances application; melanoma; nanomaterials treatment; treatment melanoma ... See more keywords