Engineering Mammalian Designer Cells for the Treatment of Metabolic Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Journal"
DOI: 10.1002/biot.201700160
Abstract: Synthetic biology applies engineering principles to biological systems and has significantly advanced the design of synthetic gene circuits that can reprogram cell activities to perform new functions. The ability to engineer mammalian designer cells with… read more here.
Keywords: designer; treatment metabolic; engineering; metabolic diseases ... See more keywords
Extended Screening Costs Associated With Selecting Donors for Fecal Microbiota Transplantation for Treatment of Metabolic Syndrome-Associated Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx243
Abstract: Abstract Background Knowledge of the impact of the gut microbiome on conditions other than Clostridium difficile infection has been rapidly increasing, and the potential usefulness of fecal microbiota transplantation (FMT) in these indications is being… read more here.
Keywords: treatment metabolic; costs associated; microbiota transplantation; metabolic syndrome ... See more keywords
Metabolic lipid muscle disorders: biomarkers and treatment
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DOI: 10.1177/1756286419843359
Abstract: Lipid storage myopathies (LSMs) are metabolic disorders of the utilization of fat in muscles due to several different defects. In this review, a molecular update of LSMs is presented and recent attempts of finding treatment… read more here.
Keywords: treatment metabolic; lipid muscle; muscle disorders; disorders biomarkers ... See more keywords
Novel Inhibitors of Nicotinamide-N-Methyltransferase for the Treatment of Metabolic Disorders
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DOI: 10.3390/molecules26040991
Abstract: Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to nicotinamide (Nam). It is expressed in many tissues including the liver, adipose tissue, and skeletal muscle. Its expression… read more here.
Keywords: treatment metabolic; methyltransferase treatment; methyltransferase; novel inhibitors ... See more keywords