Gepants for abortive treatment of migraine: A network meta‐analysis
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DOI: 10.1002/brb3.1701
Abstract: To evaluate and compare the efficacy and safety of gepants for abortive treatment of migraine by network meta‐analysis. read more here.
Keywords: treatment migraine; gepants abortive; migraine network; abortive treatment ... See more keywords
Authors’ Reply to Diener: “Phytomedicines in the Treatment of Migraine”
Sign Up to like & getrecommendations! Published in 2019 at "CNS Drugs"
DOI: 10.1007/s40263-019-00636-0
Abstract: Thank you for the opportunity to respond to Prof. Diener’s letter [1]. While the authors were aware of the referenced article in Cephalalgia Reports [2] at the time of writing, there were constraints placed on… read more here.
Keywords: migraine; treatment migraine; migraine authors; product ... See more keywords
Oral rimegepant for preventive treatment of migraine: a phase 2/3, randomised, double-blind, placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2021 at "The Lancet"
DOI: 10.1016/s0140-6736(20)32544-7
Abstract: BACKGROUND Rimegepant is a calcitonin gene-related peptide receptor antagonist that has shown efficacy and safety in the acute treatment of migraine. We aimed to compare the efficacy of rimegepant with placebo for preventive treatment of… read more here.
Keywords: placebo; double blind; migraine; treatment migraine ... See more keywords
Acute treatment of migraine: quo vadis?
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1329821
Abstract: Migraine represents the third cause of disability in the worldwide population aged under 50 years. Facing this enormous social impact, only onabotulinumtoxinA has been evaluated, on serendipity basis, as effective chronic migraine preventative treatment [1].… read more here.
Keywords: migraine; treatment migraine; quo vadis; treatment ... See more keywords
Fremanezumab for the preventive treatment of migraine
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2019.1627323
Abstract: ABSTRACT Introduction: The recent approval of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway introduced the first preventive treatments for migraine that were specifically designed to target the underlying pathophysiology of the disease. Fremanezumab,… read more here.
Keywords: migraine; treatment migraine; preventive treatments; migraine fremanezumab ... See more keywords
Phase 3 randomized, placebo-controlled, double-blind study of lasmiditan for acute treatment of migraine
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DOI: 10.1093/brain/awz134
Abstract: Lasmiditan is a selective 5-HT1F receptor agonist without vasoconstrictive activity. In this phase 3 double-blind placebo-controlled study, Goadsby et al. show that lasmiditan is efficacious and relatively well tolerated in the acute treatment of migraine… read more here.
Keywords: phase; treatment migraine; placebo controlled; acute treatment ... See more keywords
Combining Guided Intervention of Education and Relaxation (GIER) with Remote Electrical Neuromodulation (REN) in the Acute Treatment of Migraine.
Sign Up to like & getrecommendations! Published in 2022 at "Pain medicine"
DOI: 10.1093/pm/pnac021
Abstract: BACKGROUND Evidence indicates that combining behavioral treatments with pharmacological treatments for migraine prevention improves efficacy, however little is known about the outcomes of combining neuromodulation and behavioral interventions for acute treatment of migraine. Remote Electrical… read more here.
Keywords: migraine; treatment migraine; remote electrical; intervention ... See more keywords
Optimized Acute Treatment of Migraine Is Associated With Greater Productivity in People With Migraine
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Occupational and Environmental Medicine"
DOI: 10.1097/jom.0000000000002801
Abstract: Migraine reduces the ability to work and to function optimally at work. Suboptimal acute treatment for migraine attacks is linked to greater lost productive time. Optimizing an individual’s acute treatment for migraine may reduce migraine-related… read more here.
Keywords: migraine; treatment migraine; acute treatment; treatment ... See more keywords
Interim results of a prospective, randomized, open-label, Phase 3 study of the long-term safety and efficacy of lasmiditan for acute treatment of migraine (the GLADIATOR study)
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DOI: 10.1177/0333102419864132
Abstract: Objectives To address the need for long-term lasmiditan data, the GLADIATOR study evaluated the safety (primary) and efficacy (secondary) of lasmiditan for the intermittent, acute treatment of migraine attacks for up to 1 year. Methods… read more here.
Keywords: treatment migraine; long term; treatment; study ... See more keywords
Guidelines of the International Headache Society for clinical trials with neuromodulation devices for the treatment of migraine
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DOI: 10.1177/03331024211010413
Abstract: Background Although the European Medicines Agency and the US Food and Drug Administration have cleared several devices that use neuromodulation to provide clinical benefits in the acute or preventive treatment of migraine, the Clinical Trials… read more here.
Keywords: treatment migraine; treatment; clinical trials; neuromodulation devices ... See more keywords
Efficacy, safety and indirect comparisons of lasmiditan, rimegepant, and ubrogepant for the acute treatment of migraine: A systematic review and network meta-analysis of the literature
Sign Up to like & getrecommendations! Published in 2023 at "Cephalalgia"
DOI: 10.1177/03331024231151419
Abstract: Background We performed a random-effects network meta-analysis to study the efficacy and safety of newly developed drugs for the acute treatment of migraine attacks. Methods MEDLINE via PubMed, Embase and The Cochrane Register of Controlled… read more here.
Keywords: meta analysis; efficacy; treatment migraine; treatment ... See more keywords