Targeted synthesis and biological activity of polypharmacophoric agents for the treatment of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2017 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-017-1953-y
Abstract: Synthetic approaches to the design of new multitarget agents for the treatment of neurodegenerative diseases are surveyed. These approaches are based on the conjugation of the pharmacophoric indole, phenothiazine, and aminoadamantane moieties via 1-oxopropylene and… read more here.
Keywords: agents treatment; treatment neurodegenerative; neurodegenerative diseases; biological activity ... See more keywords
The Therapeutic Potential of Mesenchymal Stem Cell–Derived Exosomes in Treatment of Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-01663-0
Abstract: Neurologic complications are commonly regarded as irreversible impairments that stem from limited potential of regeneration of the central nervous system (CNS). On the other side, the regenerative potential of stem cells has been evaluated in… read more here.
Keywords: exosomes treatment; treatment neurodegenerative; stem; cell ... See more keywords
The therapeutic potential of galectin-1 and galectin-3 in the treatment of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2020.1750955
Abstract: ABSTRACT Introduction: Neuroinflammation has been proposed as a common factor and one of the main inducers of neuronal degeneration. Galectins are a group of β-galactoside-binding lectins, that play an important role in the immune response,… read more here.
Keywords: galectin galectin; galectin; neurodegenerative diseases; treatment neurodegenerative ... See more keywords
Epigenetic Treatment of Neurodegenerative Ophthalmic Disorders: An Eye Toward the Future
Sign Up to like & getrecommendations! Published in 2017 at "BioResearch Open Access"
DOI: 10.1089/biores.2017.0036
Abstract: Abstract Eye disease is one of the primary medical conditions that requires attention and therapeutic intervention in ageing populations worldwide. Further, the global burden of diabetes and obesity, along with heart disease, all lead to… read more here.
Keywords: ophthalmic disorders; epigenetic treatment; disorders eye; treatment neurodegenerative ... See more keywords
Nanoformulations of Herbal Extracts in Treatment of Neurodegenerative Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00238
Abstract: Nanotechnology is one of the methods that influenced human life in different ways and is a substantial approach that assists to overcome the multiple limitations of various diseases, particularly neurodegenerative disorders (NDs). Diverse nanostructures such… read more here.
Keywords: treatment; neurodegenerative disorders; nanoformulations herbal; extracts treatment ... See more keywords
Adamantanes for the treatment of neurodegenerative diseases in the presence of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1128157
Abstract: Advent of the acute respiratory coronavirus SARS-CoV-2 has resulted in the search for novel antiviral agents and in the repurposing of existing agents with demonstrated efficacy against other known coronaviruses in the search for an… read more here.
Keywords: treatment neurodegenerative; diseases presence; adamantanes treatment; treatment ... See more keywords
Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01165
Abstract: Effective treatments for neurodegenerative diseases need to be developed. MiR132 is abundantly expressed in the brain, and it modulates neuron morphology and plays a key role in maintaining neuron survival. Regulating miR132 can effectively improve… read more here.
Keywords: mir132; delivery; neurodegenerative diseases; treatment neurodegenerative ... See more keywords
Berberine: A Promising Treatment for Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.845591
Abstract: Berberine, as a natural alkaloid compound, is characterized by a diversity of pharmacological effects. In recent years, many researches focused on the role of berberine in central nervous system diseases. Among them, the effect of… read more here.
Keywords: promising treatment; treatment neurodegenerative; disease; berberine promising ... See more keywords
Transcranial near-infrared light in treatment of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.965788
Abstract: Light is a natural agent consisting of a range of visible and invisible electromagnetic spectrum travels in waves. Near-infrared (NIR) light refers to wavelengths from 800 to 2,500 nm. It is an invisible spectrum to… read more here.
Keywords: treatment neurodegenerative; near infrared; brain; neurodegenerative diseases ... See more keywords
Plant-Based Antioxidants for Prevention and Treatment of Neurodegenerative Diseases: Phytotherapeutic Potential of Laurus nobilis, Aronia melanocarpa, and Celastrol
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030746
Abstract: With the progress of medicine, especially in the last century, life expectancy increased considerably. As a result, age-related diseases also increased, especially malignancies and degenerative diseases of the central nervous system. The incidence and prevalence… read more here.
Keywords: based antioxidants; prevention treatment; treatment neurodegenerative; plant based ... See more keywords
Screening and Structure–Activity Relationship of D2AAK1 Derivatives for Potential Application in the Treatment of Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072239
Abstract: Neurodegenerative and mental diseases are serious medical, economic and social problems. Neurodegeneration is referred to as a pathological condition associated with damage to nerve cells leading to their death. Treatment of neurodegenerative diseases is at… read more here.
Keywords: d2aak1 derivatives; structure activity; treatment neurodegenerative; treatment ... See more keywords