Cartilage matrix-inspired biomimetic superlubricated nanospheres for treatment of osteoarthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119931
Abstract: The superlubrication of natural joint has been attributed to hydration lubrication of articular cartilage. Here, inspired by the structure of phosphatidylcholine lipid (a typical cartilage matrix) with the presence of zwitterionic charges, we developed superlubricated… read more here.
Keywords: cartilage matrix; superlubricated nanospheres; drug; cartilage ... See more keywords
Serum insulin in pathogenesis and treatment of osteoarthritis.
Sign Up to like & getrecommendations! Published in 2017 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2016.12.010
Abstract: Osteoarthritis (OA) is one of the major health problems that's development and progression is obesity-related. We believe that higher levels of insulin may explains this link especially. High levels of insulin in obesity and metabolic… read more here.
Keywords: serum insulin; insulin pathogenesis; treatment; osteoarthritis ... See more keywords
Potential role of nutraceuticals via targeting a Wnt/β-catenin and NF-κB pathway in treatment of osteoarthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14427
Abstract: Osteoarthritis (OA) is a disease due to the aging of the articular cartilage, a post-mitotic tissue that stays functioning until primary homeostatic processes fail. Because of pain and disability, OA significantly influences national healthcare expenses… read more here.
Keywords: wnt catenin; catenin; treatment osteoarthritis; catenin pathway ... See more keywords
Tanezumab for the treatment of osteoarthritis pain.
Sign Up to like & getrecommendations! Published in 2022 at "Drugs of today"
DOI: 10.1358/dot.2022.58.4.3352752
Abstract: Tanezumab is a novel humanized IgG2 monoclonal antibody that works by selectively targeting, binding to and inhibiting nerve growth factor (NGF). NGF is upregulated in response to injury and inflammation, and preclinical data indicate it… read more here.
Keywords: treatment osteoarthritis; osteoarthritis pain; pain; tanezumab treatment ... See more keywords
Immunoregulation of synovial macrophages for the treatment of osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0567
Abstract: Abstract Osteoarthritis (OA) is the most common joint disease affecting approximately 10% of men and 18% of women older than 60. Its pathogenesis is still not fully understood; however, emerging evidence has suggested that chronic… read more here.
Keywords: treatment osteoarthritis; macrophages treatment; immunoregulation synovial; synovial macrophages ... See more keywords
High Tibial Osteotomies for the Treatment of Osteoarthritis of the Knee.
Sign Up to like & getrecommendations! Published in 2022 at "JBJS reviews"
DOI: 10.2106/jbjs.rvw.21.00127
Abstract: » A high tibial osteotomy (HTO) is a joint-preserving procedure that can be used to treat symptomatic unicompartmental cartilage disorders in the presence of limb malalignment. » Appropriate patient selection and careful preoperative planning are… read more here.
Keywords: treatment osteoarthritis; high tibial; tibial osteotomies; osteotomies treatment ... See more keywords
GEL-MAN Hydrogel Loaded With Triamcinolone Acetonide for the Treatment of Osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00872
Abstract: One of the major challenges for the treatment of osteoarthritis (OA) with therapeutic drugs is the short half-life of drugs in the joint cavity. The severity of OA often fluctuates with time and inflammatory factors.… read more here.
Keywords: hydrogel loaded; man; gel man; treatment osteoarthritis ... See more keywords
Hydrogels for Treatment of Different Degrees of Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.858656
Abstract: Osteoarthritis (OA) is a common disease that severely restricts human activities and degrades the quality of life. Every year, millions of people worldwide are diagnosed with osteoarthritis, placing a heavy burden on society. Hydrogels, a… read more here.
Keywords: treatment different; treatment osteoarthritis; hydrogels treatment; treatment ... See more keywords
The Involvement of Neutrophils in the Pathophysiology and Treatment of Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071604
Abstract: Osteoarthritis (OA) is a chronic disability that significantly impairs quality of life. OA is one of the most prevalent joint pathologies in the world, characterized by joint pain and stiffness due to the degeneration of… read more here.
Keywords: treatment osteoarthritis; neutrophils pathophysiology; pathophysiology treatment; osteoarthritis ... See more keywords