UK clinical guideline for the prevention and treatment of osteoporosis
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DOI: 10.1007/s11657-017-0324-5
Abstract: IntroductionIn 2008, the UK National Osteoporosis Guideline Group (NOGG) produced a guideline on the prevention and treatment of osteoporosis, with an update in 2013. This paper presents a major update of the guideline, the scope… read more here.
Keywords: guideline; treatment osteoporosis; guideline prevention; prevention treatment ... See more keywords
Bone-targeting parathyroid hormone conjugates outperform unmodified PTH in the anabolic treatment of osteoporosis in rats
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DOI: 10.1007/s13346-017-0407-2
Abstract: Synthetic parathyroid hormone (PTH) is clinically indicated for the treatment of osteoporosis, through its anabolic effects on parathyroid hormone receptors (PTHRs), located on osteoblast cells. However, the bioavailability of PTH for bone cells is restricted… read more here.
Keywords: pth; bone targeting; parathyroid hormone; treatment osteoporosis ... See more keywords
Pathophysiology and treatment of osteoporosis: challenges for clinical practice in older people
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DOI: 10.1007/s40520-021-01817-y
Abstract: Osteoporosis, a common chronic metabolic bone disease is associated with considerable morbidity and mortality. As the prevalence of osteoporosis increases with age, a paralleled elevation in the rate of incident fragility fractures will be observed.… read more here.
Keywords: older people; pathophysiology treatment; treatment osteoporosis; osteoporosis challenges ... See more keywords
Exploring the mechanism of action Xianlingubao Prescription in the treatment of osteoporosis by network pharmacology
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DOI: 10.1016/j.compbiolchem.2020.107240
Abstract: In this study, the network pharmacology analysis method was used to explore the bioactive components and targets of Xianlinggubao (XLGB) and further elucidate its potential biological mechanisms of action in the treatment of osteoporosis (OP).… read more here.
Keywords: medicine; pharmacology; treatment osteoporosis; network pharmacology ... See more keywords
08 Evidence Base for Treatment of Osteoporosis in Older People
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DOI: 10.1093/ageing/afz164.08
Abstract: After the age of fifty years the prevalence of osteoporosis and incidence of osteoporotic fractures rise substantially with age. It is ironic however that the pivotal trials for the common drugs used to treat osteoporosis… read more here.
Keywords: reduction; age; treatment osteoporosis; evidence ... See more keywords
Effects of teriparatide compared with risedronate in the treatment of osteoporosis
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DOI: 10.1097/md.0000000000019042
Abstract: Abstract Background: This meta-analysis was conducted to compare the effects and safety of teriparatide with risedronate in the treatment of osteoporosis. Material and methods: PubMed, Embase, Web of Science and Cochrane library database were systematically… read more here.
Keywords: wmd 001; risedronate treatment; treatment osteoporosis; fracture ... See more keywords
Minodronate in the treatment of osteoporosis
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DOI: 10.1097/md.0000000000022542
Abstract: Abstract Background: The goal of this study was to review relevant randomized controlled trials or case-control studies to determine the clinical efficacy of minodronate in the treatment of osteoporosis. Method: The relevant studies were identified… read more here.
Keywords: minodronate treatment; treatment osteoporosis; minodronate; bap wmd ... See more keywords
Bibliometric and visual analysis of mesenchymal stem cells in the treatment of osteoporosis based on CiteSpace software
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DOI: 10.1097/md.0000000000031859
Abstract: Background: The focus of research in the treatment of osteoporosis (OP) has evolved from promoting bone formation and inhibiting bone resorption to current stem cell therapy. Due to their multipotent differentiation properties, mesenchymal stem cells… read more here.
Keywords: treatment osteoporosis; bone; analysis; stem ... See more keywords
Mechanism of Pilose Antler in Treatment of Osteoporosis Based on Network Pharmacology
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DOI: 10.1155/2022/5298892
Abstract: Background The purpose of this study was to demonstrate the pharmacodynamic material basis and molecular mechanism of pilose antler (PA) in the prevention and treatment of osteoporosis (OP) by the method of network pharmacology. Methods… read more here.
Keywords: network; treatment osteoporosis; pharmacology; pilose antler ... See more keywords
Combined low-dose LiCl and LY294002 for the treatment of osteoporosis in ovariectomized rats
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DOI: 10.1186/s13018-019-1210-1
Abstract: BackgroundTo provide a low-toxicity and high-efficacy clinical treatment for osteoporosis via a novel combination of LiCl and LY294002.MethodsThe protein levels of p-AKT, AKT, p-GSK3β, GSK3β, β-catenin, p-β-catenin, and NFATC1 were measured in osteoblasts and osteoclasts… read more here.
Keywords: licl ly294002; treatment osteoporosis; low dose; licl ... See more keywords
Factors that cause women with osteoporosis to fall.
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DOI: 10.20945/2359-3997000000578
Abstract: Objective To analyze and compare intrinsic and extrinsic factors that cause falls among women receiving treatment for osteoporosis. Subjects and methods A cross-sectional study of women ≥50 years receiving treatment for osteoporosis. Participants filled out… read more here.
Keywords: treatment osteoporosis; faller group; receiving treatment; factors cause ... See more keywords