A Hydrogen Peroxide Activatable Gemcitabine Prodrug for the Selective Treatment of Pancreatic Ductal Adenocarcinoma
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DOI: 10.1002/cmdc.201900324
Abstract: The main concern in the use of anticancer chemotherapeutic drugs is host toxicity. Patients need to interrupt or change chemotherapy due to adverse effects. In this study, we aimed to decrease adverse events with gemcitabine… read more here.
Keywords: gem; hydrogen peroxide; treatment; pancreatic ductal ... See more keywords
3D planning of irreversible electroporation treatment in pancreatic carcinoma: a use case
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DOI: 10.1016/j.hpb.2018.06.2299
Abstract: Irreversible-electroporation (IRE) is an ablation technique that spares vessels and is therefore suitable for treatment of locally advanced pancreatic cancer. Our surgery planning software supports pre-operative simulation of possible needle configurations in 3D to prepare… read more here.
Keywords: irreversible electroporation; treatment; electroporation treatment; treatment pancreatic ... See more keywords
N-arylpiperazine-containing compound (C2): An enhancer of sunitinib in the treatment of pancreatic cancer, involving D1DR activation.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114789
Abstract: Previous studies showed that dopamine (DA) significantly reduces the frequency of cancer stem-like cells (CSC) and enhances the efficacy of sunitinib (SUN) in the treatment of breast cancer and non-small cell lung cancer (NSCLC). To… read more here.
Keywords: containing compound; arylpiperazine containing; pancreatic cancer; cancer ... See more keywords
Overcoming diagnostic issues in precision treatment of pancreatic cancer
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DOI: 10.1080/23808993.2018.1476061
Abstract: ABSTRACT Introduction: With high-throughput DNA analysis with next-generation sequencing (NGS), a new area of comprehensive molecular diagnostics is entering clinic. The profile of biomarkers (mutations and other abnormalities) may lay the foundation for precision treatment.… read more here.
Keywords: analysis; treatment; overcoming diagnostic; precision treatment ... See more keywords
Endoscopic versus surgical treatment for pancreatic pseudocysts
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DOI: 10.1097/md.0000000000014255
Abstract: Objective: This systematic review and meta-analysis aims to compare surgical and endoscopic treatment for pancreatic pseudocyst (PP). Methods: The researchers did a search in Medline, EMBASE, Scielo/Lilacs, and Cochrane electronic databases for studies comparing surgical… read more here.
Keywords: treatment pancreatic; endoscopic; treatment; surgical endoscopic ... See more keywords
Analysis of the Effect of Robots in the Treatment of Pancreatic Cancer Based on Smart Medicine
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DOI: 10.1155/2021/9734882
Abstract: In order to study the effect of robots in the treatment of pancreatic cancer in the context of smart medical, this paper improves the robot recognition technology and data processing technology and improves the system… read more here.
Keywords: effect; medicine; treatment pancreatic; pancreatic cancer ... See more keywords
Abstract B50: Keratin 17 drives tumor aggression and could be targeted for treatment of pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.panca19-b50
Abstract: Our aims are to uncover the molecular mechanisms through which keratin 17 (K17), a prognostic biomarker, drives tumor aggression and to target these mechanisms to provide more effective treatment for pancreatic ductal adenocarcinoma (PDAC). In… read more here.
Keywords: k17; drives tumor; treatment; tumor aggression ... See more keywords
Chemoprevention and Treatment of Pancreatic Cancer: Update and Review of the Literature
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DOI: 10.1159/000485741
Abstract: Background: Pancreatic ductal adenocarcinoma is one of the most lethal types of cancer with a 5-year survival rate of around 7%. Due to the relatively poor prognosis, the potential need of an effective chemoprevention is… read more here.
Keywords: cancer update; pancreatic cancer; cancer; treatment pancreatic ... See more keywords
Surgical-only treatment of pancreatic and extra-pancreatic metastases from renal cell carcinoma - quality of life and survival analysis
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DOI: 10.1186/s12893-020-00757-0
Abstract: Background Treatment of pancreatic metastases (PM) from renal cell carcinoma (RCC) is still an issue between surgeons and oncologists, in the era of target-therapy. Methods Data from 26 patients undergoing resection of PM and extra-PM… read more here.
Keywords: renal cell; pancreatic metastases; cell carcinoma; pancreatic extra ... See more keywords
The involvement of exosomes in the diagnosis and treatment of pancreatic cancer
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DOI: 10.1186/s12943-020-01245-y
Abstract: At the moment, pancreatic cancer is among the deadliest gastrointestinal diseases, and pancreatic cancer growth is a complex biological process that is based on different kinds of genes. Exosomes are extracellular vesicles containing microRNAs (miRNAs),… read more here.
Keywords: cancer involvement; diagnosis treatment; pancreatic cancer; cancer ... See more keywords
Use of phenotypic profiling to determine sensitivity of gemcitabine with nab-paclitaxel for front-line treatment of pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e15749
Abstract: e15749Background: Standard of care treatment for pancreatic adenocarcinoma (PDAC) consists of FOLFIRINOX (FFX) or gemcitabine with nab-paclitaxel (G/nab-P) in the front-line setting. The decision t... read more here.
Keywords: front line; nab paclitaxel; treatment pancreatic; gemcitabine nab ... See more keywords