Notch-HEY2 signaling pathway contributes to the differentiation of CD34+ hematopoietic-like stem cells from adult peripheral blood insulin-producing cells after the treatment with platelet-derived mitochondria
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DOI: 10.1007/s11033-020-05874-w
Abstract: Previous works characterized a novel cell population from adult human peripheral blood, designated peripheral blood insulin-producing cells (PB-IPC). PB-IPC displayed the pluripotent potential of differentiations after the treatment with platelet-derived mitochondria and gave rise to… read more here.
Keywords: treatment; derived mitochondria; signaling pathway; peripheral blood ... See more keywords
Impact of high on-treatment platelet reactivity after angioplasty in patients with critical limb ischemia.
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DOI: 10.1016/j.vph.2021.106925
Abstract: OBJECTIVES Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard of care in patients with peripheral artery disease (PAD) after percutaneous transluminal angioplasty (PTA). However, high on treatment platelet reactivity (HTPR) to DAPT is… read more here.
Keywords: patients critical; high treatment; limb; htpr ... See more keywords
Net platelet clot strength of thromboelastography platelet mapping assay for the identification of high on-treatment platelet reactivity in post-PCI patients
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DOI: 10.1042/bsr20201346
Abstract: Abstract High-on treatment platelet reactivity (HTPR) leads to more prevalence of thrombotic event in patients undergoing percutaneous coronary interventions (PCI). Dual antiplatelet therapy with aspirin in addition to one P2Y12 inhibitor is commonly administrated to… read more here.
Keywords: high treatment; treatment; platelet reactivity; platelet mapping ... See more keywords
Impact of high on-treatment platelet reactivity after angioplasty in patients with peripheral arterial disease
Sign Up to like & getrecommendations! Published in 2020 at "Platelets"
DOI: 10.1080/09537104.2020.1742314
Abstract: Abstract Objective: High on-treatment platelet reactivity (HTPR) to dual antiplatelet therapy (DAPT) predicts adverse events in coronary artery disease patients. In peripheral artery disease (PAD) patients, data concerning the clinical impact of HTPR are limited.… read more here.
Keywords: high treatment; treatment; disease; platelet reactivity ... See more keywords
Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on-treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)-2 Trial.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of haematology"
DOI: 10.1111/bjh.17847
Abstract: High on-treatment platelet reactivity (HOPR) is associated with increased risk of cardiovascular events in patients undergoing percutaneous coronary intervention (PCI). We randomised post-PCI patients with HOPR after 5 days of standard dual antiplatelet therapy (DAPT) to… read more here.
Keywords: high treatment; antiplatelet therapy; therapy; treatment platelet ... See more keywords
Generation of Hematopoietic-Like Stem Cells from Adult Human Peripheral Blood Following Treatment with Platelet-Derived Mitochondria
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21124249
Abstract: Adult stem cells represent a potential source for cellular therapy to treat serious human diseases. We characterized the insulin-producing cells from adult peripheral blood (designated PB-IPC), which displayed a unique phenotype. Mitochondria are normally located… read more here.
Keywords: peripheral blood; blood; cells adult; stem ... See more keywords