Autophagy pathways in the treatment of prion diseases.
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DOI: 10.1016/j.coph.2019.04.013
Abstract: Prions use cellular machineries for autocatalytic propagation by conformational conversion of the cellular prion protein into the pathological isoform PrPSc. Autophagy is a basic cellular degradation and recycling machinery that delivers cargo to lysosomes. Increase… read more here.
Keywords: prion; treatment prion; pharmacology; prion diseases ... See more keywords