[Diagnosis and treatment of pulmonary embolism].
Sign Up to like & getrecommendations! Published in 2021 at "Herz"
DOI: 10.1007/s00059-021-05078-3
Abstract: Pulmonary embolism (PE) frequently presents a diagnostic and therapeutic challenge in the clinical practice. Established diagnostic algorithms enable the prevention of unnecessary use of imaging with ionizing radiation, so that now standardized algorithms could also be… read more here.
Keywords: diagnosis treatment; treatment; pulmonary embolism; treatment pulmonary ... See more keywords
Guidelines for the Treatment of Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Lung"
DOI: 10.1007/s00408-020-00375-w
Abstract: Pulmonary arterial hypertension (PAH) is a rare form of pulmonary hypertension characterized by a progressive obliterative vasculopathy of the distal pulmonary arterial circulation that usually leads to right ventricular failure and death. Over the last… read more here.
Keywords: arterial hypertension; treatment; pulmonary arterial; guidelines treatment ... See more keywords
Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112259
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening and interstitial lung disease with the median survival of only 3-5 years. However, due to the unclear etiology and problems in accurate diagnosis, up to now only… read more here.
Keywords: fibrosis; tgf smad; smad dependent; pulmonary fibrosis ... See more keywords
Nebulized solid lipid nanoparticles for the potential treatment of pulmonary hypertension via targeted delivery of phosphodiesterase-5-inhibitor.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2016.12.026
Abstract: Phosphodiesterase type 5 (PDE-5) inhibitors - among which sildenafil citrate (SC) - play a primary role in the treatment of pulmonary hypertension (PH). Yet, SC can be only administered orally or parenterally with lot of… read more here.
Keywords: pulmonary hypertension; delivery; lipid nanoparticles; targeted delivery ... See more keywords
Linezolid as treatment for pulmonary Mycobacterium avium disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx304
Abstract: Objectives To identify the pharmacokinetic/pharmacodynamic parameters and exposures of linezolid in the treatment of pulmonary Mycobacterium avium complex (MAC) disease. Methods Human-derived monocytes infected with MAC were inoculated into hollow-fibre systems for dose-effect and dose-scheduling… read more here.
Keywords: treatment pulmonary; pulmonary mycobacterium; linezolid treatment; mycobacterium avium ... See more keywords
Advances in the Study of Inhaled Formulations for the Treatment of Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Applied Bionics and Biomechanics"
DOI: 10.1155/2022/6495645
Abstract: Pulmonary arterial hypertension (PAH) is a serious disease with reduced systemic circulation and low bioavailability associated with conventional and dosed therapy, which inhaled drugs can avoid. A mean pulmonary artery pressure (mPAP) of ≥25 mmHg (1 mmHg… read more here.
Keywords: pulmonary hypertension; arterial hypertension; hypertension; pulmonary arterial ... See more keywords
Treatment of pulmonary arterial hypertension with the dual endothelin receptor antagonist macitentan: clinical evidence and experience
Sign Up to like & getrecommendations! Published in 2019 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/1753466618823440
Abstract: Macitentan (10 mg once daily orally), a dual endothelin receptor antagonist (ERA) developed by modifying the structure of bosentan to increase the efficacity and safety, is approved for the treatment of pulmonary arterial hypertension (PAH). The… read more here.
Keywords: receptor antagonist; trial; treatment; dual endothelin ... See more keywords
Macitentan in the treatment of pulmonary hypertension in Gaucher’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Anatolian Journal of Cardiology"
DOI: 10.14744/anatoljcardiol.2019.23096
Abstract: Gaucher’s disease (GD) is a rare disease characterized by a lysosomal β glucosidase enzyme deficiency. Although the etiology of pulmonary hypertension in this condition cannot be clearly determined, the disease itself, splenectomy treatment and enzyme… read more here.
Keywords: gaucher disease; pulmonary hypertension; treatment; hypertension ... See more keywords
DPP-4 Inhibitors in the Prevention/Treatment of Pulmonary Fibrosis, Heart and Kidney Injury Caused by COVID-19—A Therapeutic Approach of Choice in Type 2 Diabetic Patients?
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01185
Abstract: Since the outbreak of SARS-CoV-2 virus more than 12,500,000 cases have been reported worldwide. Patients suffering from diabetes and other comorbidities are particularly susceptible to severe forms of the COVID-19, which might result in chronic… read more here.
Keywords: heart kidney; dpp inhibitors; pulmonary fibrosis; prevention treatment ... See more keywords
Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.607689
Abstract: Idiopathic Pulmonary Fibrosis (IPF) is a chronically progressive interstitial lung that affects over 3 M people worldwide and rising in incidence. With a median survival of 2–3 years, IPF is consequently associated with high morbidity,… read more here.
Keywords: mesenchymal transition; fibrosis; transition; epithelial mesenchymal ... See more keywords
Comparative Effectiveness of Methotrexate versus Methylprednisolone in Treatment Naïve Pulmonary Sarcoidosis Patients
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11081401
Abstract: Among those who study granulomatous diseases, sarcoidosis is of tremendous interest, not only because its cause is unknown, but also because it is still as much an enigma today as it was 150 years ago… read more here.
Keywords: versus methylprednisolone; methotrexate versus; methylprednisolone treatment; comparative effectiveness ... See more keywords