Global distribution of treatment resistance gene markers for leishmaniasis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24599
Abstract: Pentavalent antimonials (Sb(V)) such as meglumine antimoniate (Glucantime®) and sodium stibogluconate (Pentostam®) are used as first‐line treatments for leishmaniasis, either alone or in combination with second‐line drugs such as amphotericin B (Amp B), miltefosine (MIL),… read more here.
Keywords: gene markers; distribution treatment; treatment resistance; resistance gene ... See more keywords
Analysis of predictive factors for treatment resistance and disease relapse in Takayasu’s arteritis
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DOI: 10.1007/s10067-018-4094-2
Abstract: The objective of the study was to investigate the long-term treatment effects and predictive factors for treatment response and disease relapse for Takayasu’s arteritis (TA). Eighty-one patients were recruited from the Department of Rheumatology, Zhongshan… read more here.
Keywords: treatment; disease; treatment resistance; rheumatology ... See more keywords
Risk factors for treatment resistance and relapse of Chinese patients with MPO-ANCA-associated vasculitis
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DOI: 10.1007/s10238-020-00614-7
Abstract: Identification of risk factors for treatment resistance and relapse would be crucial to personalization therapy in patients with myeloperoxidase (MPO)-anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (MPO-AAV). Current evidence with regard to the risk factors for treatment… read more here.
Keywords: relapse; risk; resistance relapse; treatment resistance ... See more keywords
Overcoming treatment resistance in cancer: Current understanding and tactics.
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DOI: 10.1016/j.canlet.2016.04.018
Abstract: Chemotherapy is the standard treatment for many, if not all, metastatic cancers. While chemotherapy is often capable of inducing cell death in tumors leading to shrinkage of the tumor bulk, many patients suffer from recurrence… read more here.
Keywords: treatment; treatment resistance; overcoming treatment; resistance cancer ... See more keywords
Studying treatment resistance in depression using patient derived neurons in vitro
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DOI: 10.1038/s41380-019-0424-2
Abstract: Fig. 1 Stylized artistic images of forebrain neurons derived from iPSCs of antidepressant (SSRI) resistant depressed patients. Neurons from SSRI-resistant patients display differential activity in response to serotonin, downstream of key excitatory serotonergic receptors, highlighting… read more here.
Keywords: studying treatment; depression using; treatment resistance; resistance ... See more keywords
Treatment resistance in psychiatry: state of the art and new directions
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Psychiatry"
DOI: 10.1038/s41380-021-01200-3
Abstract: Treatment resistance affects 20–60% of patients with psychiatric disorders; and is associated with increased healthcare burden and costs up to ten-fold higher relative to patients in general. Whilst there has been a recent increase in… read more here.
Keywords: disorder; resistance; treatment resistance; resistance psychiatry ... See more keywords
Structural Covariance of Cortical Gyrification at Illness Onset in Treatment Resistance: A Longitudinal Study of First-Episode Psychoses
Sign Up to like & getrecommendations! Published in 2021 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbab035
Abstract: Abstract Treatment resistance (TR) in patients with first-episode psychosis (FEP) is a major cause of disability and functional impairment, yet mechanisms underlying this severe disorder are poorly understood. As one view is that TR has… read more here.
Keywords: gyrification; first episode; treatment resistance; structural covariance ... See more keywords
The impact of treatment resistance on outcome and course of electroconvulsive therapy in major depressive disorder
Sign Up to like & getrecommendations! Published in 2023 at "Acta Psychiatrica Scandinavica"
DOI: 10.1111/acps.13550
Abstract: Major depressive disorder (MDD) is a common psychiatric disorder. Despite several treatment options, a subgroup of patients will not respond to the commonly used antidepressant treatments and thus express treatment resistance (TRD). TRD can be… read more here.
Keywords: outcome; treatment resistance; treatment; disorder ... See more keywords
Treatment Resistance in Bipolar Affective Disorder with Recurrent Mania Course - Role of Periventricular Leukomalacia.
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DOI: 10.1111/bdi.13138
Abstract: A 34-year-old married female, educated up to grade 12, living as a homemaker in an urban area, presented to us for a clinical evaluation with a four-day history of manic symptoms along with auditory hallucinations… read more here.
Keywords: affective disorder; bipolar affective; treatment resistance; disorder recurrent ... See more keywords
Association of cortical thickness and cognition with schizophrenia treatment resistance
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DOI: 10.1111/pcn.13486
Abstract: Approximately a third of patients with schizophrenia fail to adequately respond to antipsychotic medications, a condition known as treatment resistance (TR). We aimed to assess cognitive and cortical thickness deficits and their relationship to TR… read more here.
Keywords: treatment resistance; schizophrenia; cortical thickness;
IL33 Is a Key Driver of Treatment Resistance of Cancer
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DOI: 10.1158/0008-5472.can-19-2235
Abstract: These findings indicate that the functional role of IL33 in cancer polyploidy contributes to intrinsic and extrinsic mechanisms underlying treatment failure. Recurrence and treatment resistance are major causes of cancer-associated death. There has been a… read more here.
Keywords: treatment; cancer; treatment resistance; il33 key ... See more keywords