One-Year Outcomes Following Intravenous Ketamine Plus Digital Training Among Patients with Treatment-Resistant Depression
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.12434
Abstract: This secondary analysis of a randomized clinical trial examines whether automated self-association training can prolong the antidepressant effect of a single infusion of ketamine beyond 1 month in patients with treatment-resistant depression. read more here.
Keywords: resistant depression; patients treatment; training; treatment resistant ... See more keywords
Association of Treatment-Resistant Depression With Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2022.3860
Abstract: This cohort study examines data for episodes of unipolar major depressive disorder that met criteria for treatment-resistant depression to assess its impact on individuals and society and consider potential prognostic factors. read more here.
Keywords: resistant depression; study; association treatment; treatment resistant ... See more keywords
Effectiveness of electroconvulsive therapy in patients with “less treatment‐resistant” depression by the Maudsley Staging Model
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DOI: 10.1002/brb3.1654
Abstract: Electroconvulsive therapy (ECT) is an effective treatment for patients with mood disorders and is most often used for treatment‐resistant cases. This study aimed to examine the effectiveness of ECT in a real‐world treatment sample in… read more here.
Keywords: treatment resistant; effectiveness electroconvulsive; treatment; electroconvulsive therapy ... See more keywords
Finding factors that predict treatment‐resistant depression: Results of a cohort study
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DOI: 10.1002/da.22774
Abstract: Treatment for depressive disorders often requires subsequent interventions. Patients who do not respond to antidepressants have treatment‐resistant depression (TRD). Predicting who will develop TRD may help healthcare providers make more effective treatment decisions. We sought… read more here.
Keywords: treatment resistant; finding factors; treatment; resistant depression ... See more keywords
A pilot study of magnetic seizure therapy for treatment‐resistant obsessive–compulsive disorder
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DOI: 10.1002/da.23097
Abstract: There is growing interest in the potential of neuromodulation options in treatment‐resistant obsessive–compulsive disorder (OCD). Magnetic seizure therapy (MST), is a new treatment intervention in which generalized seizures are induced with transcranial magnetic stimulation. We… read more here.
Keywords: treatment resistant; compulsive disorder; obsessive compulsive; magnetic seizure ... See more keywords
Changes in white matter microstructure following serial ketamine infusions in treatment resistant depression
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DOI: 10.1002/hbm.26217
Abstract: Ketamine produces fast‐acting antidepressant effects in treatment resistant depression (TRD). Though prior studies report ketamine‐related changes in brain activity in TRD, understanding of ketamine's effect on white matter (WM) microstructure remains limited. We thus sought… read more here.
Keywords: resistant depression; white matter; matter microstructure; depression ... See more keywords
Serum level of soluble interleukin 6 receptor is a useful biomarker for identification of treatment‐resistant major depressive disorder
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12100
Abstract: A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation. Identifying treatment‐resistant major depressive disorder patients before the… read more here.
Keywords: resistant major; treatment resistant; depressive disorder; treatment ... See more keywords
Efficacy of clozapine for long‐stay patients with treatment‐resistant schizophrenia: 4‐year observational study
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DOI: 10.1002/npr2.12244
Abstract: Supporting patients upon discharge following prolonged hospitalization in private psychiatric hospitals in Japan have long been an issue. This study evaluated the efficacy of clozapine in treating long‐stay patients with treatment‐resistant schizophrenia to reduce the… read more here.
Keywords: resistant schizophrenia; efficacy clozapine; stay patients; treatment resistant ... See more keywords
Novel therapies for treatment of resistant and refractory nontuberculous mycobacterial infections in patients with cystic fibrosis
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DOI: 10.1002/ppul.24939
Abstract: Respiratory infections caused by non‐tuberculous mycobacteria (NTM) are a major cause of morbidity for patients living with cystic fibrosis (CF), as NTM pulmonary disease (NTM‐PD) is challenging to both diagnose and eradicate. Despite the lengthy… read more here.
Keywords: cystic fibrosis; treatment resistant; fibrosis; novel therapies ... See more keywords
Esketamine nasal spray for treatment‐resistant depression
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DOI: 10.1002/psb.1845
Abstract: A nasal spray formulation of esketamine (Spravato) was licensed as adjunctive therapy for the management of adults with treatment‐resistant major depression in December. This article discusses the properties, clinical trial efficacy and adverse effects of… read more here.
Keywords: treatment; treatment resistant; esketamine; nasal spray ... See more keywords
Is twice daily LF-rTMS a viable treatment option for treatment-resistant OCD? Results from an open-label feasibility study
Sign Up to like & getrecommendations! Published in 2020 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-020-01142-x
Abstract: Several reports point to the beneficial effects of repetitive transcranial magnetic stimulation (rTMS) in the treatment of resistant obsessive–compulsive disorder (OCD). This study aimed to evaluate the safety and efficacy of rTMS targeting the dmPFC… read more here.
Keywords: treatment resistant; treatment; twice daily; resistant ocd ... See more keywords